Is Galactooligosaccharides safe in cosmetics?
Galactooligosaccharides has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Galactooligosaccharides
Also known as: 2H-Pyran-2-one, 6-pentyl-, 5-Hydroxy-2,4-decadienoic acid delta-lactone, 6-Pentyl-2H-pyran-2-one, EINECS 248-552-3, FEMA No. 3696 (+3 more)
INCI: GALACTOOLIGOSACCHARIDES
Galactooligosaccharides (CAS 27593-23-3) is a cosmetic cosmetic ingredient functioning as Skin conditioning, humectant; prebiotic. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 27593-23-3 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, humectant; prebiotic
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
6-pentylpyran-2-one
InChIKey
MAUFTTLGOUBZNA-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — GRAS status (FDA GRAS Notice GRN 671)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Galactooligosaccharides.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
deodorant
{"cas_number": "6587-31-1", "ingredient_class": "prebiotic_deodorant", "mechanism_of_action": "microbiome_modulation", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "12-24", "odor_reduction_pct": "40-60", "bacteriostatic": "no", "bactericidal": "no", "target_bacteria": "promotes beneficial", "microbiome_impact": "prebiotic", "axillary_microbiome_effect": "varies b…
microbiome
{"ingredient_class": "prebiotic", "live_organism_content": "no", "bioactive_components": "oligosaccharides", "molecular_weight_range_Da": "500-2000", "pH_of_ingredient": "5.5-7.0", "mechanism_of_action": "competitive_exclusion", "skin_microbiome_effect": "balancing", "scalp_microbiome_effect": "balancing", "anti_aging_mechanism": "barrier_repair", "skin_barrier_improvement": "moderate", "TEWL_redu…
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (1)
JECFA Evaluation
5-HYDROXY-2,4-DECADIENOIC ACID delta-LACTONE | 1997 | NOT EVALUATED | Evaluation postponed pending consideration of other alpha, beta-unsaturated carbonyl compounds | TRS 884-JECFA 49/42 | FAS 40-JECFA 49/231
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Galactooligosaccharides.
Regulatory Flags
potential-allergen
ifra_fragrance
fda_food_additive
Known Synonyms
2H-Pyran-2-one, 6-pentyl-
5-Hydroxy-2,4-decadienoic acid delta-lactone
6-Pentyl-2H-pyran-2-one
EINECS 248-552-3
FEMA No. 3696
6-Pentyl-alpha-pyrone
6-Pentyl-2-pyrone
UNII-8JTW8HL4PJ
Chemical Function
Flavouring and nutrient
Fragrance
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL503899
Frequently Asked Questions
Is Galactooligosaccharides allowed in the EU?
Galactooligosaccharides EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Galactooligosaccharides do in cosmetics?
Galactooligosaccharides functions as: Skin conditioning, humectant; prebiotic. It is classified as a cosmetic ingredient in our database. CAS number: 27593-23-3.
Is Galactooligosaccharides used outside cosmetics?
Galactooligosaccharides also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Galactooligosaccharides compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
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GALIUM VERUM EXTRACT
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Good
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