What is the NOAEL for 6-Pentyl-2H-pyran-2-one?
6-Pentyl-2H-pyran-2-one has 4 NOAEL studies in the database. The lowest reported value is 8JTW8HL4PJ UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
6-Pentyl-2H-pyran-2-one
Also known as: 2H-Pyran-2-one, 6-pentyl-, 5-Hydroxy-2,4-decadienoic acid delta-lactone, EINECS 248-552-3, FEMA No. 3696, 6-Pentyl-alpha-pyrone (+2 more)
CAS 27593-23-3
6-Pentyl-2H-pyran-2-one (CAS 27593-23-3) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
6-Pentyl-2H-pyran-2-one
CAS Number
27593-23-3
DTXSID
DTXSID0047589
Molecular Formula
C10H14O2
InChI Key
MAUFTTLGOUBZNA-UHFFFAOYSA-N
Monoisotopic Mass
166.09938
Synonyms
2H-Pyran-2-one, 6-pentyl-5-Hydroxy-2,4-decadienoic acid delta-lactoneEINECS 248-552-3FEMA No. 36966-Pentyl-alpha-pyrone6-Pentyl-2-pyroneUNII-8JTW8HL4PJ
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Flavouring and nutrientFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 8JTW8HL4PJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8JTW8HL4PJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8JTW8HL4PJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8JTW8HL4PJ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Humectant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL503899
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: NOT EVALUATED mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 6-Pentyl-2H-pyran-2-one?
6-Pentyl-2H-pyran-2-one appears on 3 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe. Source: EPA CPDat.
Is 6-Pentyl-2H-pyran-2-one used in cosmetics?
Yes, 6-Pentyl-2H-pyran-2-one is also indexed as a cosmetic ingredient under the name Galactooligosaccharides. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 6-Pentyl-2H-pyran-2-one come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 6-Pentyl-2H-pyran-2-one used outside industrial chemicals?
6-Pentyl-2H-pyran-2-one also appears in cosmetics, pharmaceutical, food safety, cannabis databases.