Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st
Also known as: Eucalyptus oil, Oils, eucalyptus, Caswell No. 618A, EPA Pesticide Chemical Code 040503, Eucalyptus absolute (+13 more)
INCI: EUCALYPTUS GLOBULUS LEAF OIL
Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st (CAS 8000-48-4) is a cosmetic emollient functioning as Emollient. Reported NOAEL =100 mg/kg bw/day in rat (CIR_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
For full compliance data across multiple jurisdictions, use the
Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st.
Calculate MoS for your specific formulation with the
MoS Calculator.
Toxicological Studies
10 study endpoints found for Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
Endpoint
Value
Route
Species
Study Type
Source
NOAEL
=100 mg/kg bw/day
-
rat
NOAEL study
CIR_vision_codex
NOAEL
=100 mg/kg bw/day
-
rat
NOAEL study
CIR_vision_codex
NOAEL
=100 mg/kg bw/day
-
rat
NOAEL study
CIR_vision_codex
NOAEL
=100 mg/kg bw/day
-
rat
NOAEL study
CIR_vision_codex
NOAEL
=300 mg/kg
oral
rat
oral toxicity
CIR_vision_codex
NOAEL
=300 mg/kg
oral
rat
oral toxicity
CIR_vision_codex
NOAEL
=300 mg/kg
oral
rat
oral toxicity
CIR_vision_codex
NOAEL
=300 mg/kg
oral
rat
oral toxicity
CIR_vision_codex
NOAEL
=1000 mg/kg
oral
rat
oral toxicity
CIR_vision_codex
NOAEL
=1000 mg/kg
oral
rat
oral toxicity
CIR_vision_codex
EPA ToxValDB — Toxicity Values
3 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
Endpoint
Value
Species
Route
Duration
Source
LD50
<5000 mg/kg
Rabbit
dermal
acute
ECHA IUCLID
LD50
=2480 mg/kg
Rabbit
dermal
acute
ECHA IUCLID
LD50
=2480 mg/kg
Rat
oral
-
TEST
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
Jurisdiction
Status
Max %
Product Type
CA
restricted
25%
All cosmetics
Additional Ingredient Properties
1 property record from structured ingredient metadata.
BiocideDeodorizerFlavouring and nutrientFragranceHumectantPharmaceuticalSoftener and conditioner
Regulatory List Membership (5)
EU Regulated in Personal CareEU Restricted for Children (Cosmetics)IFRA Fragrance Transparency ListFDA Substances Added to Food (EAFUS)Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st.
IFRA TransparencyIFRA Transparencyconsumer_productIFRA TransparencyIFRA TransparencyIFRA TransparencyEurope; Personal careEurope; Personal careEurope; Personal careEurope; Personal carechildren; Europe; Personal carechildren; Europe; Personal care - specialized bath products - bubble bathIFRA Transparencyactive_ingredient; Pesticidesactive_ingredient; Pesticidesactive_ingredient; Pesticidesactive_ingredient; Pesticidesactive_ingredient; Pesticides
Australian Status
AICIS status:listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCEChEMBL / DrugCentral / FAERSDB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Is Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st safe in cosmetics?
Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.
Is Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st allowed in the EU?
Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st do in cosmetics?
Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st functions as: Emollient. It is classified as a Emollient in our database. CAS number: 8000-48-4.
What is the NOAEL for Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st?
The NOAEL (No Observed Adverse Effect Level) for Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st is =100 mg/kg bw/day based on a NOAEL study study via oral route in rat. A total of 10 study endpoints are available. Source: CIR_vision_codex.
Is Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st used outside cosmetics?
Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st compliance across multiple jurisdictions:
Is Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Eucalyptus Oil (Eucalyptus Globulus Leaf Oil) Return st in your formulation.