Moderate Cosmetic Ingredient NOAEL Data

Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine

Also known as: 1,3,5-Triazine-2,4,6-triamine, N,N'-bis(4-(5-(1,1-dimethylpropyl)-2-benzoxazolyl)phenyl)-N''-(2-ethylhexyl)-, 1,3,5-Triazine-2,4,6-triamine, N2,N4-bis(4-(5-(1,1-dimethylpropyl)-2-benzoxazolyl)phenyl)-N6-(2-ethylhexyl)-, (+/-)-Ethylhexyl bis-isopentylbenzoxazolylphenyl melamine, Ethylhexyl bis-isopentylbenzoxazolylphenyl melamine, (+/-)-

INCI: ETHYLHEXYL BIS-ISOPENTYLBENZOXAZOLYLPHENYL MELAMINE

Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine (CAS 288254-16-0) is a cosmetic cosmetic ingredient functioning as UV absorber (optical brightener / UV light stabilizer); trade name Uvasorb K2A. Reported NOAEL =1400 mg/kg bw/day in rat (SCCNFP_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 288254-16-0 →

Auto-generated CPSR Part A draft with source citations
Function
UV absorber (optical brightener / UV light stabilizer); trade name Uvasorb K2A
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C47H56N8O2
MW
765 g/mol
PubChem CID
10123230
IUPAC Name
6-N-(2-ethylhexyl)-2-N,4-N-bis[4-[5-(2-methylbutan-2-yl)-1,3-benzoxazol-2-yl]phenyl]-1,3,5-triazine-2,4,6-triamine
InChIKey
ZVIJJZZVZCQINB-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not FDA-approved as an OTC sunscreen active (not in 21 CFR 352); may be used as a product stabilizer, not as a sunscreen active

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine.

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Toxicological Studies

4 study endpoints found for Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1400 mg/kg bw/day oral rat repeated dose toxicity SCCNFP_vision_codex
NOAEL =1400 mg/kg bw/day oral rat repeated dose toxicity SCCNFP_vision_codex
NOAEL =1400 mg/kg bw/day oral rat repeated dose toxicity SCCNFP_vision_codex
NOAEL =1400 mg/kg bw/day oral rat repeated dose toxicity SCCNFP_vision_codex

Function Categories & List Membership

Cosmetic/Chemical Function Categories
UV stabilizer

Expert Verdict

Expert safety assessment and concern-level summary for Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine.

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine by CAS number or substance name.

Studies
4
Lowest NOAEL
1400 mg/kg bw/day
Highest NOAEL
1400 mg/kg bw/day
SCCNFP_vision_codex

Known Synonyms

1,3,5-Triazine-2,4,6-triamine, N,N'-bis(4-(5-(1,1-dimethylpropyl)-2-benzoxazolyl)phenyl)-N''-(2-ethylhexyl)- 1,3,5-Triazine-2,4,6-triamine, N2,N4-bis(4-(5-(1,1-dimethylpropyl)-2-benzoxazolyl)phenyl)-N6-(2-ethylhexyl)- (+/-)-Ethylhexyl bis-isopentylbenzoxazolylphenyl melamine Ethylhexyl bis-isopentylbenzoxazolylphenyl melamine, (+/-)-

Chemical Function

UV stabilizer

Frequently Asked Questions

Is Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine safe in cosmetics?

Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 4 toxicological study endpoint(s) are available in our database.

Is Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine allowed in the EU?

Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine do in cosmetics?

Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine functions as: UV absorber (optical brightener / UV light stabilizer); trade name Uvasorb K2A. It is classified as a cosmetic ingredient in our database. CAS number: 288254-16-0.

What is the NOAEL for Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine?

The NOAEL (No Observed Adverse Effect Level) for Ethylhexyl Bis-Isopentylbenzoxazolylphenyl Melamine is =1400 mg/kg bw/day based on a repeated dose toxicity study via oral route in rat. A total of 4 study endpoints are available. Source: SCCNFP_vision_codex.

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