Is Ethyl Trisiloxane safe in cosmetics?
Ethyl Trisiloxane has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Ethyl Trisiloxane
Also known as: UNII-ZH1WJO5481
INCI: ETHYL TRISILOXANE
Ethyl Trisiloxane (CAS 17861-60-8) is a cosmetic cosmetic ingredient functioning as Skin conditioning / Emollient (silicone derivative). NOAEL 50 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 17861-60-8 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning / Emollient (silicone derivative)
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
ethyl-methyl-bis(trimethylsilyloxy)silane
InChIKey
HLPWCQDWRYCGLK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific CFR restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethyl Trisiloxane.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Ethyl Trisiloxane across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Viscosity modifier
Expert Verdict
Expert safety assessment and concern-level summary for Ethyl Trisiloxane.
Known Synonyms
UNII-ZH1WJO5481
Chemical Function
Softener and conditioner
Viscosity modifier
Australian Status
AICIS status: listed_with_terms
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.
Frequently Asked Questions
Is Ethyl Trisiloxane allowed in the EU?
Ethyl Trisiloxane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Trisiloxane do in cosmetics?
Ethyl Trisiloxane functions as: Skin conditioning / Emollient (silicone derivative). It is classified as a cosmetic ingredient in our database. CAS number: 17861-60-8.
Is Ethyl Trisiloxane used outside cosmetics?
Ethyl Trisiloxane also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ethyl Trisiloxane compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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