Is Ethyl Oleate safe in cosmetics?
Ethyl Oleate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Ethyl Oleate
Also known as: EINECS 203-889-5, Ethyl 9-octadecenoate, (Z)-, FEMA No. 2450, NSC 229428, UNII-Z2Z439864Y (+2 more)
INCI: ETHYL OLEATE
Ethyl Oleate (CAS 111-62-6) is a cosmetic cosmetic ingredient functioning as Emollient, Perfuming, Solvent, Penetration Enhancer. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 111-62-6 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient, Perfuming, Solvent, Penetration Enhancer
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
ethyl (Z)-octadec-9-enoate
InChIKey
LVGKNOAMLMIIKO-QXMHVHEDSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Listed in 21 CFR 172.515 as synthetic flavoring; no cosmetic restrictions; CIR 2015 safe-as-used for alkyl esters class
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethyl Oleate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 5400 | - | - |
Additional Ingredient Properties
2 property records from structured ingredient metadata.
emulsion_hlb
{"hlb_required_as_emulsifier": "no", "hlb_required_of_oil_phase": "10-11", "co_emulsifier_pairs": "polysorbate_80,oleth_10", "optimal_oil_phase_pct": "10-30", "optimal_water_phase_pct": "70-90", "droplet_size_range_um": "1-20", "creaming_resistance": "good", "coalescence_resistance": "good", "ostwald_ripening_resistance": "moderate", "freeze_thaw_stability": "moderate", "rheology_modifier_type": "…
sensory
{"silky": "medium", "smooth, glides easily": "smooth, silky", "dry-touch, non-greasy": "soft, smooth", "instant": "moderate", "low": "medium", "w/o": "o/w", "very-high": "high", "no": "no", "yes": "no", "light-diffusing": "luminous", "1.40": "1.45", "transparent": "transparent", "colorless": "colorless", "excellent": "good", "light": "medium", "synthetic": "botanical"}
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
345
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ETHYL OLEATE | 2019 | No safety concern at current levels of intake when used as a flavouring agent | Considered for specifications only | TRS 1020-JECFA 87/74 | FAS 42-JECFA 51/267
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Lubricating agent
Softener and conditioner
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Ethyl Oleate.
Regulatory Flags
penetration-enhancer
cir-safe
alkyl-ester
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
EINECS 203-889-5
Ethyl 9-octadecenoate, (Z)-
FEMA No. 2450
NSC 229428
UNII-Z2Z439864Y
ethyl (9Z)-octadecenoate
oleic acid ethyl ester
Chemical Function
Softener and conditioner
Fragrance
Flavouring and nutrient
Lubricating agent
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
inert_ingredient; non_food_use; Pesticides
active_ingredient; animal_products; Europe; pharmaceutical; residue
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ETHYL OLEATE
ChEMBL ID
CHEMBL2106289
Max Phase
-1
Frequently Asked Questions
Is Ethyl Oleate allowed in the EU?
Ethyl Oleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Oleate do in cosmetics?
Ethyl Oleate functions as: Emollient, Perfuming, Solvent, Penetration Enhancer. It is classified as a cosmetic ingredient in our database. CAS number: 111-62-6.
Is Ethyl Oleate used outside cosmetics?
Ethyl Oleate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ethyl Oleate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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