Is Ethyl Ethylhexanoate safe in cosmetics?
Ethyl Ethylhexanoate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Ethyl Ethylhexanoate
INCI: ETHYL ETHYLHEXANOATE
Ethyl Ethylhexanoate (CAS 2983-37-1) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent, emollient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 2983-37-1 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent, emollient
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
ethyl 2-ethylhexanoate
InChIKey
YXAGIRHBJJLWHW-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no CFR restriction; CIR assessed safe as used
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethyl Ethylhexanoate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 8100 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (1)
JECFA Number
2285
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Ethyl Ethylhexanoate.
Regulatory Flags
ifra_fragrance
fda_food_additive
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
ETHYL 2-ETHYLHEXANOATE
ADI
No safety concern at current levels of intake when used as a flavouring agentt mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Ethyl Ethylhexanoate allowed in the EU?
Ethyl Ethylhexanoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Ethylhexanoate do in cosmetics?
Ethyl Ethylhexanoate functions as: Skin conditioning agent, emollient. It is classified as a cosmetic ingredient in our database. CAS number: 2983-37-1.
Is Ethyl Ethylhexanoate used outside cosmetics?
Ethyl Ethylhexanoate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ethyl Ethylhexanoate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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