Is Ethoxyethyl Methacrylate safe in cosmetics?
Ethoxyethyl Methacrylate has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
Ethoxyethyl Methacrylate
Also known as: 2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester, EINECS 219-135-3, Methacrylic acid, 2-ethoxyethyl ester, NSC 24162, UNII-5Q6XR4MR8E
INCI: ETHOXYETHYL METHACRYLATE
Ethoxyethyl Methacrylate (CAS 2370-63-0) is a cosmetic cosmetic ingredient functioning as Film forming; artificial nail builder. NOAEL 163 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 2370-63-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Ethoxyethyl Methacrylate is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H335, H360, H360FD).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Film forming; artificial nail builder
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-ethoxyethyl 2-methylprop-2-enoate
InChIKey
SFPNZPQIIAJXGL-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Allowed. CIR Expert Panel concluded it is safe as used in nail enhancement products when accompanied by directions to avoid skin contact.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethoxyethyl Methacrylate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Ethoxyethyl Methacrylate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Film former
Expert Verdict
Expert safety assessment and concern-level summary for Ethoxyethyl Methacrylate.
Regulatory Flags
potential-allergen
Known Synonyms
2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester
EINECS 219-135-3
Methacrylic acid, 2-ethoxyethyl ester
NSC 24162
UNII-5Q6XR4MR8E
Chemical Function
Film former
Regulatory Lists
Europe; Personal care - nails
detected; Europe; Personal care - nails - nail polish
Australian Status
AICIS status: listed_with_terms
Specific information requirements: Obligations to provide information apply. You must tell the Executive Director the volume of introduction, use and end use of the chemical within 20 working days if: ; the chemical is being introduced for consumer end use except in articles.
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1414186
Frequently Asked Questions
Is Ethoxyethyl Methacrylate allowed in the EU?
Ethoxyethyl Methacrylate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethoxyethyl Methacrylate do in cosmetics?
Ethoxyethyl Methacrylate functions as: Film forming; artificial nail builder. It is classified as a cosmetic ingredient in our database. CAS number: 2370-63-0.
Is Ethoxyethyl Methacrylate used outside cosmetics?
Ethoxyethyl Methacrylate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Ethoxyethyl Methacrylate have different safety status in cosmetics vs industrial chemicals?
Ethoxyethyl Methacrylate is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H335, H360, H360FD).
Compliance Tools
Check Ethoxyethyl Methacrylate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acrylates/Vinyl Neodecanoate Crosspolymer
Excellent
Same category
Emulsion stabilising, film forming
Adipic Acid
Excellent
Same category
Buffering
Aluminum Magnesium Oxide
Excellent
Same category
Absorbent, bulking agent, opacifying ...
Ammonium VA/Acrylates Copolymer
Excellent
Same category
Antistatic, binding, film forming, ha...
Ammonium VA/Crotonic Acid Copolymer
Excellent
Same category
Antistatic, film forming, hair fixing...
Aphanothece Sacrum Polysaccharide
Excellent
Same category
Absorbent, emulsion stabilising, film...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
Ethoxyethyl Methacrylate (2-Ethoxyethyl Methacrylate)
Moderate
Chemical family
Film former / nail enhancement monomer
ETHOXY-METHOXYMETHYL-PHENOL
Good
Browse nearby
Perfuming
ETHOXYDIGLYCOL ACETATE
Good
Browse nearby
Solvent
Is Ethoxyethyl Methacrylate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ethoxyethyl Methacrylate in your formulation.