Is Ethane safe in cosmetics?
Ethane has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted.
Ethane
Also known as: EINECS 200-814-8, UNII-L99N5N533T, R-170
INCI: ETHANE
Ethane (CAS 74-84-0) is a cosmetic cosmetic ingredient functioning as Propellant. EU Regulation 1223/2009 status: restricted; GHS signal word DANGER. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 74-84-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Ethane is classified GHS Danger (H220, H280, H281, H336) in the chemicals database but is restricted in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Chemistry & Identifiers
IUPAC Name
ethane
InChIKey
OTMSDBZUPAUEDD-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Permitted — 21 CFR 170.3 lists as GRAS; no cosmetic-specific restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethane.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Signal Word
DANGER
Pictograms
FlamFlameCylinderGas
Hazard Statements
Extremely flammable gas Contains gas under pressure; may explode if heated
Short-term Exposure Effects
Rapid evaporation of the liquid may cause frostbite.
Routes of Exposure
The substance can be absorbed into the body by inhalation.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Danger
Pictograms
FlammableCompressed Gas
Hazard Class and Category
Flam. Gas 1; Press. Gas
Hazard Statements
- H220 Extremely flammable gas
Inserted via ATP: CLP00
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100,000 - 1,000,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
ICSC Safety Card
0266
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Skin Eye Respiratory Irritation
Not irritating to eyes, nose, or throat.
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Propellants
non-motive (blowing agents)
Expert Verdict
Expert safety assessment and concern-level summary for Ethane.
Known Synonyms
EINECS 200-814-8
UNII-L99N5N533T
R-170
Chemical Function
Propellants
non-motive (blowing agents)
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ETHANE
ChEMBL ID
CHEMBL135626
Max Phase
2
Frequently Asked Questions
Is Ethane allowed in the EU?
Ethane EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethane do in cosmetics?
Ethane functions as: Propellant. It is classified as a cosmetic ingredient in our database. CAS number: 74-84-0.
Is Ethane classified as hazardous under GHS?
Ethane carries a GHS signal word of "DANGER". Hazard statements: Extremely flammable gas Contains gas under pressure; may explode if heated. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Is Ethane used outside cosmetics?
Ethane also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Ethane have different safety status in cosmetics vs industrial chemicals?
Ethane is classified GHS Danger (H220, H280, H281, H336) in the chemicals database but is restricted in EU cosmetics.
Compliance Tools
Check Ethane compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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