Good Cosmetic Ingredient NOAEL Data

DM HYDANTOIN

Also known as: 2,4-Imidazolidinedione, 5,5-dimethyl-, Dantoin DMH, NSC 8652, Dantoin 736, 5,5-Dimethyl-2,4-imidazolidinedione (+12 more)

DM HYDANTOIN (CAS 77-71-4) is a cosmetic cosmetic ingredient functioning as Hair Conditioning, Viscosity Controlling. Reported NOAEL =23.4 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 77-71-4 →

Auto-generated CPSR Part A draft with source citations
Function
Hair Conditioning, Viscosity Controlling
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C5H8N2O2
MW
128.13 g/mol
EC Number
201-051-3
PubChem CID
6491
IUPAC Name
5,5-dimethylimidazolidine-2,4-dione
InChIKey
YIROYDNZEPTFOL-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status Not specifically regulated

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Toxicological Studies

1 study endpoint found for DM HYDANTOIN. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =23.4 mg/kg bw/day oral Rat chronic ToxValDB_ECHA_IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Softener and conditioner Surfactant (surface active agent) Viscosity modifier

Expert Verdict

Expert safety assessment and concern-level summary for DM HYDANTOIN.

Regulatory Flags

cosing-sourced eu-permitted hair-conditioning needs-enrichment

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to DM HYDANTOIN by CAS number or substance name.

Studies
1
Lowest NOAEL
23.4 mg/kg bw/day
Highest NOAEL
23.4 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

2,4-Imidazolidinedione, 5,5-dimethyl- Dantoin DMH NSC 8652 Dantoin 736 5,5-Dimethyl-2,4-imidazolidinedione 5,5-Dimethyl-Imidazolidine-2,4-dione 4,4-Dimethyl-2,5-dioxoimidazolidine Fennosurf 300 Hydantoin, 5,5-dimethyl- 5,5-dimethylhydantoin EC No.: 201-051-3 5-24-05-00348 BRN 0002827 Dimethylhydantoin EINECS 201-051-3 UNII-34032MQ9RO DMH

Chemical Function

Surfactant (surface active agent) Viscosity modifier Softener and conditioner

Regulatory Lists

Arts and crafts/Office supplies - home office - pens and markers; detected; Europe inert_ingredient; non_food_use; Pesticides

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

ChEMBL ID
CHEMBL3181806
View full pharmaceutical profile →

Frequently Asked Questions

Is DM HYDANTOIN safe in cosmetics?

DM HYDANTOIN has a safety rating of "GOOD" in our database. EU status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is DM HYDANTOIN allowed in the EU?

DM HYDANTOIN EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does DM HYDANTOIN do in cosmetics?

DM HYDANTOIN functions as: Hair Conditioning, Viscosity Controlling. It is classified as a cosmetic ingredient in our database. CAS number: 77-71-4.

What is the NOAEL for DM HYDANTOIN?

The NOAEL (No Observed Adverse Effect Level) for DM HYDANTOIN is =23.4 mg/kg bw/day based on a chronic study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is DM HYDANTOIN used outside cosmetics?

DM HYDANTOIN also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Related Ingredients

ACETYL TRIPEPTIDE-45 D-PHENYLALANYL OCTAPEPTIDE-14 NORLEUCYL PENTAPEPTIDE-38 METHYL LEUCYL DECAPEPTIDE-26 NORLEUCYL GLUTAMYL METHYL LEUCYL ISOLEUCINAMIDE
Good Same category
Hair Conditioning
AVENA SATIVA FLOWER/LEAF/STEM EXTRACT
Good Same category
Hair Conditioning
BABASSUAMIDOPROPALKONIUM CHLORIDE
Good Same category
Antistatic, Hair Conditioning
BEHENYL HYDROXYETHYL IMIDAZOLINE
Good Same category
Antistatic, Hair Conditioning
BIS-CETEARAMIDOETHYLDIETHONIUM SUCCINOYL HYDROLYZED KERATIN
Good Same category
Hair Conditioning
BIS-DIMONIUM METHOSULFATE
Good Same category
Emulsion Stabilising, Hair Conditioning
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good Similar safety
Antioxidant
Acetyl Tributyl Citrate
Good Chemical family
Plasticizer; solvent; film-former
Acetyl Triethyl Citrate
Excellent Chemical family
Film Forming, Plasticiser, Masking, P...
Beta-Santalol
Moderate Chemical family
Fragrance

Is DM HYDANTOIN in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for DM HYDANTOIN in your formulation.