Is Dipotassium Oxalate safe in cosmetics?
Dipotassium Oxalate has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.
Poor
Cosmetic Ingredient
Dipotassium Oxalate
Also known as: EINECS 209-506-8, Potassium neutral oxalate, UNII-LC7F2W7I5B
INCI: DIPOTASSIUM OXALATE
Dipotassium Oxalate (CAS 583-52-8) is a cosmetic cosmetic ingredient functioning as Chelating agent (industrial/analytical use; not a standard cosmetic ingredient). NOAEL 162 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 583-52-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Dipotassium Oxalate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H319, H315, H318, H335, H373).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Chelating agent (industrial/analytical use; not a standard cosmetic ingredient)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
dipotassium;oxalate
InChIKey
IRXRGVFLQOSHOH-UHFFFAOYSA-L
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Not specifically listed in 21 CFR cosmetic prohibitions, but the GHS classification (H302+H312) and acute oral toxicity (LD50 oral rat ~16 mg/kg) would make inclusion in cosmetics untenable under MoCRA safety substantiation requirements
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dipotassium Oxalate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Dipotassium Oxalate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Chelating agent
Corrosion inhibitor
Expert Verdict
Expert safety assessment and concern-level summary for Dipotassium Oxalate.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Dipotassium Oxalate by CAS number or substance name.
Studies
3
Lowest NOAEL
162 mg/kg bw/day
Highest NOAEL
162 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
EINECS 209-506-8
Potassium neutral oxalate
UNII-LC7F2W7I5B
Chemical Function
Chelating agent
Corrosion inhibitor
Regulatory Lists
Canada; consumer_product; Substances in Products - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Dipotassium Oxalate allowed in the EU?
Dipotassium Oxalate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Dipotassium Oxalate do in cosmetics?
Dipotassium Oxalate functions as: Chelating agent (industrial/analytical use; not a standard cosmetic ingredient). It is classified as a cosmetic ingredient in our database. CAS number: 583-52-8.
Is Dipotassium Oxalate used outside cosmetics?
Dipotassium Oxalate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Dipotassium Oxalate have different safety status in cosmetics vs industrial chemicals?
Dipotassium Oxalate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H312, H319, H315, H318, H335, H373).
Compliance Tools
Check Dipotassium Oxalate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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