NOAEL Studies Cosmetic Ingredient

Diisononyl Adipate NOAEL Studies

CAS: 33703-08-1

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_endocrine 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_endocrine Model Score 0 unitless - - - ARPathway2016; AR Pathway Model, Antagonist sheet=Integrated_approaches; excel_row=8120; RecordID=ARPathway2016_1155; DatasetName=ARPathway2016; DTXSID=DTXSID5027982; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID5027982
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =8.9 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15631658:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_53818db6fd29d45fd87bfa817f14c2b7
ToxValDB_HPVIS 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_HPVIS NOAEL ~274 mg/kg bw/day Dog oral subchronic; 13 weeks subchronic LONG_REF=Unpublished confidential business information. Diisononyl Adipate: 90-Day Dietary Administration in Dogs.; TITLE=Diisononyl Adipate: 90-Day Dietary Administration in Dogs; QUALITY=1; EXTERNAL_SOURCE_ID=61600; EXTERNAL_SOURCE_ID_DESC=HPVIS ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/63861d6de4b04f6bb1480596; RECORD_SOURCE_LEVEL=Extraction document; YEAR=1971; ORIGINAL_YEAR=1971; STUDY_GROUP=HPVIS:15639198:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_0f6226a94a0829d74166f4d269cefb3b
ToxValDB_HPVIS NOAEL =500 mg/kg bw/day Rat oral subchronic; 13 weeks subchronic LONG_REF=Unpublished confidential business information. Diisononyl Adipate: 90-Day Dietary Administration in Rats.; TITLE=Diisononyl Adipate: 90-Day Dietary Administration in Rats; QUALITY=1; EXTERNAL_SOURCE_ID=62629; EXTERNAL_SOURCE_ID_DESC=HPVIS ID; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/63861d6de4b04f6bb1480596; RECORD_SOURCE_LEVEL=Extraction document; YEAR=1971; ORIGINAL_YEAR=1971; STUDY_GROUP=HPVIS:15639319:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_1481ef117a14cd614fe3169f145fde9b
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier BMQ5JF4857 UNII - - - chemical {"approval_status":null,"molecular_formula":"C24H46O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"BMQ5JF4857"}
openFDA substances FDA UNII substance identifier BMQ5JF4857 UNII - - - chemical {"approval_status":null,"molecular_formula":"C24H46O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"BMQ5JF4857"}
openFDA substances FDA UNII substance identifier BMQ5JF4857 UNII - - - chemical {"approval_status":null,"molecular_formula":"C24H46O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"BMQ5JF4857"}
openFDA substances FDA UNII substance identifier BMQ5JF4857 UNII - - - chemical {"approval_status":null,"molecular_formula":"C24H46O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"BMQ5JF4857"}