NOAEL Studies
Cosmetic Ingredient
Diisodecyl Adipate NOAEL Studies
INCI: DIISODECYL ADIPATE
CAS: 27178-16-1
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
NTP_ICE_endocrine 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_endocrine | Model Score | 0 | unitless | - | - | - | ARPathway2016; AR Pathway Model, Antagonist | sheet=Integrated_approaches; excel_row=8104; RecordID=ARPathway2016_1087; DatasetName=ARPathway2016; DTXSID=DTXSID1027924; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1027924 |
ToxValDB_ECHA_IUCLID 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | NOAEL | =178 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaae0e4b0a7c65d1b7d5c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/16083/7/9/2?documentUUID=3f83b194-2c09-4d57-879b-aec3973f0225; YEAR=2002; ORIGINAL_YEAR=2002; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855481_15856750_15856927:M:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_48b9d4fd53737322eaa838a98372843b |
| ToxValDB_ECHA_IUCLID | NOAEL | =203 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaae0e4b0a7c65d1b7d5c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/16083/7/9/2?documentUUID=3f83b194-2c09-4d57-879b-aec3973f0225; YEAR=2002; ORIGINAL_YEAR=2002; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15856295_15856885_15856934:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_289cbd1d6ee21fa2b509b4b16809656b |
| ToxValDB_ECHA_IUCLID | NOAEL | >=2102 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaae0e4b0a7c65d1b7d5c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/16083/7/9/2?documentUUID=3f83b194-2c09-4d57-879b-aec3973f0225; YEAR=2002; ORIGINAL_YEAR=2002; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855481_15856750_15856927:M:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_e8ab641af19f8d9d2feb9162a6ae4df4 |
| ToxValDB_ECHA_IUCLID | NOAEL | >=2399 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaae0e4b0a7c65d1b7d5c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/16083/7/9/2?documentUUID=3f83b194-2c09-4d57-879b-aec3973f0225; YEAR=2002; ORIGINAL_YEAR=2002; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15856295_15856885_15856934:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_81cb67b52c9036ad718bd24a88af2958 |
ToxValDB_GESTIS_DNEL 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_GESTIS_DNEL | DNEL systemic | =2.8 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15631275:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_44323c7a967143fd45173ef815a53fcf |
openFDA substances 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | 3V0Q382O0P | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C26H50O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3V0Q382O0P"} |
| openFDA substances | FDA UNII substance identifier | 3V0Q382O0P | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C26H50O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3V0Q382O0P"} |
| openFDA substances | FDA UNII substance identifier | 3V0Q382O0P | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C26H50O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3V0Q382O0P"} |
| openFDA substances | FDA UNII substance identifier | 3V0Q382O0P | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C26H50O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3V0Q382O0P"} |