NOAEL Studies Cosmetic Ingredient

Diethylenetriamine Pentamethylene Phosphonic Acid NOAEL Studies

INCI: DIETHYLENETRIAMINE PENTAMETHYLENE PHOSPHONIC ACID

CAS: 15827-60-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =312 mg/kg bw/day Rat oral - reproduction developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac1ae4b0a7c65d1bd56f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/16011/7/9/3?documentUUID=1bd1e767-4be3-4528-af30-c0e100609809; YEAR=1972; ORIGINAL_YEAR=1972; STUDY_GROUP=ECHA IUCLID:15823646:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_d44c9c2ada0bf1db02e9b26df9f5929f
ToxValDB_ECHA_IUCLID NOAEL ~936 mg/kg bw/day Rat oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaae0e4b0a7c65d1b7dfb; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/16011/7/9/2?documentUUID=1bd1e767-4be3-4528-af30-c0e100609809; YEAR=1972; ORIGINAL_YEAR=1972; STUDY_GROUP=ECHA IUCLID:15860844:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_8f951565682d9d0c5705eef40fed7f56
ToxValDB_ECHA_IUCLID NOAEL ~294 mg/kg bw/day Rat oral - developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaae0e4b0a7c65d1b7dfb; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/16011/7/9/2?documentUUID=1bd1e767-4be3-4528-af30-c0e100609809; YEAR=1972; ORIGINAL_YEAR=1972; STUDY_GROUP=ECHA IUCLID:15860897:M:F1-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_c06a4276e1835c43f7b9659dc24e8bb1
ToxValDB_ECHA_IUCLID NOAEL ~882 mg/kg bw/day Rat oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaae0e4b0a7c65d1b7dfb; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/16011/7/9/2?documentUUID=1bd1e767-4be3-4528-af30-c0e100609809; YEAR=1972; ORIGINAL_YEAR=1972; STUDY_GROUP=ECHA IUCLID:15862130:M:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_a44f84dd95581266995c9ff195b14ce2
ToxValDB_GESTIS_DNEL 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL local =10 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15634144_15634145:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_7942e78e83fe463f50418f71949908fb
ToxValDB_GESTIS_DNEL DNEL systemic =7.27 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15634144_15634145:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_f8d9a1f0541661f2ebfc095b4aaf82eb
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 0Q75589TM3 UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H28N3O15P5","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"0Q75589TM3"}
openFDA substances FDA UNII substance identifier 0Q75589TM3 UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H28N3O15P5","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"0Q75589TM3"}
openFDA substances FDA UNII substance identifier 0Q75589TM3 UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H28N3O15P5","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"0Q75589TM3"}
openFDA substances FDA UNII substance identifier 0Q75589TM3 UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H28N3O15P5","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"0Q75589TM3"}