Is Dibromopropamidine Diisethionate safe in cosmetics?
Dibromopropamidine Diisethionate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Dibromopropamidine Diisethionate
Also known as: Dibromopropamidina, Dibrompropamidinum, UNII-269M3QL74S
INCI: DIBROMOPROPAMIDINE DIISETHIONATE
Dibromopropamidine Diisethionate (CAS 496-00-4) is a cosmetic cosmetic ingredient functioning as Preservative (antimicrobial, diamidine class). EU Regulation 1223/2009 status: permitted, max 0.1%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 496-00-4 →
Auto-generated CPSR Part A draft with source citations
Function
Preservative (antimicrobial, diamidine class)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3-bromo-4-[3-(2-bromo-4-carbamimidoylphenoxy)propoxy]benzenecarboximidamide
InChIKey
GMJFVGRUYJHMCO-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
EU Max Conc.
0.1%
US US Status
permitted
US Notes
Permitted — not prohibited under 21 CFR; also used in OTC ophthalmic preparations
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dibromopropamidine Diisethionate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Expert Verdict
Expert safety assessment and concern-level summary for Dibromopropamidine Diisethionate.
Regulatory Flags
preservative
Known Synonyms
Dibromopropamidina
Dibrompropamidinum
UNII-269M3QL74S
Regulatory Lists
pharmaceutical
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
DIBROMPROPAMIDINE
ChEMBL ID
CHEMBL30044
Max Phase
2
Frequently Asked Questions
Is Dibromopropamidine Diisethionate allowed in the EU?
Dibromopropamidine Diisethionate EU regulatory status: permitted. Maximum allowed concentration: 0.1%. This is based on EU Regulation 1223/2009 and its amendments.
What does Dibromopropamidine Diisethionate do in cosmetics?
Dibromopropamidine Diisethionate functions as: Preservative (antimicrobial, diamidine class). It is classified as a cosmetic ingredient in our database. CAS number: 496-00-4.
Is Dibromopropamidine Diisethionate used outside cosmetics?
Dibromopropamidine Diisethionate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Dibromopropamidine Diisethionate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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