Is Dextran Sulfate safe in cosmetics?
Dextran Sulfate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Dextran Sulfate
Also known as: Dextran, hydrogen sulfate, Dextran sulfuric acid, Dextran polysulfate, Polydextran sulfate, Dextran sulfate 500 (+13 more)
INCI: DEXTRAN SULFATE
Dextran Sulfate (CAS 9042-14-2) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Binding, Film Forming, Viscosity Controlling. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 9042-14-2 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning, Binding, Film Forming, Viscosity Controlling
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA cosmetic restrictions. Listed in FDA GSRS with multiple MW variants. CIR group assessment (2012) concluded safe at reported use concentrations of 0.005%-0.5%.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dextran Sulfate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Binder
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Dextran Sulfate.
Regulatory Flags
cir-safe
no-sccs-opinion
no-eu-max
no-mos-calculated
data-gap-absorption
mw-dependent-behavior
Known Synonyms
Dextran, hydrogen sulfate
Dextran sulfuric acid
Dextran polysulfate
Polydextran sulfate
Dextran sulfate 500
Dextran sulphate
Dextran sulfate 5000
Sulfopolyglucin
UNII-AIW09WL51K
Dextran sulfuric acid ester
PF 51
MDS-Kowa
T 500
NSC 620255
PF 51 (carbohydrate)
Polyglucin, sulfate
DS 5000
NM 3014
Chemical Function
Softener and conditioner
Binder
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Dextran Sulfate allowed in the EU?
Dextran Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dextran Sulfate do in cosmetics?
Dextran Sulfate functions as: Skin Conditioning, Binding, Film Forming, Viscosity Controlling. It is classified as a cosmetic ingredient in our database. CAS number: 9042-14-2.
Compliance Tools
Check Dextran Sulfate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Amorphophallus Konjac Root Extract
Excellent
Same category
Film-forming agent and humectant deri...
Arabinogalactan
Excellent
Same category
Film former, emulsion stabilizer, hum...
Astragalus Gummifer Gum
Excellent
Same category
viscosity increasing agent-aqueous, b...
Cassia Angustifolia Seed Polysaccharide
Excellent
Same category
Skin conditioning agent; film-forming...
Cyclodextrin
Excellent
Same category
Absorbent, Carrier, Encapsulant, Solu...
Dextran
Excellent
Same category
Binding, Viscosity Controlling
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
PEG-9 Diethylmonium Chloride
Poor
Chemical family
Antistatic agent; hair conditioning a...
PPG-25 Diethylmonium Chloride
Poor
Chemical family
Antistatic agent; hair conditioning a...
PPG-40 Diethylmonium Chloride
Poor
Chemical family
Antistatic agent; Hair conditioning a...
Is Dextran Sulfate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Dextran Sulfate in your formulation.