Is Delta-Octalactone safe in cosmetics?
Delta-Octalactone has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Delta-Octalactone
Also known as: 2H-Pyran-2-one, tetrahydro-6-propyl-, 5-17-09-00068, BRN 0111515, EINECS 211-820-5, FEMA No. 3214 (+7 more)
INCI: DELTA-OCTALACTONE
Delta-Octalactone (CAS 698-76-0) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 698-76-0 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
6-propyloxan-2-one
InChIKey
FYTRVXSHONWYNE-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — FEMA GRAS 3214; no CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Delta-Octalactone.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 8100 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
228
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
5-HYDROXYOCTANOIC ACID LACTONE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/42 | FAS 40-JECFA 49/231
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
delta-OCTALACTONE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/42 | FAS 40-JECFA 49/231
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Delta-Octalactone.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
2H-Pyran-2-one, tetrahydro-6-propyl-
5-17-09-00068
BRN 0111515
EINECS 211-820-5
FEMA No. 3214
5-Hydroxyoctanoic acid lactone
5-Octalactone
Octanoic acid, 5-hydroxy-, lactone
5-Octanolide
5-Propyl-5-hydroxypentanoic acid lactone
delta-Propyl-delta-valerolactone
UNII-8AA944C37V
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3182050
Frequently Asked Questions
Is Delta-Octalactone allowed in the EU?
Delta-Octalactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Delta-Octalactone do in cosmetics?
Delta-Octalactone functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 698-76-0.
Is Delta-Octalactone used outside cosmetics?
Delta-Octalactone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Delta-Octalactone compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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