Is Decylamine Oxide safe in cosmetics?
Decylamine Oxide has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Decylamine Oxide
Also known as: Capric dimethyl amine oxide, 1-Decanamine, N,N-dimethyl-, N-oxide, EINECS 220-020-5, UNII-G387VUT5EZ, Decyl dimethyl amine oxide (+3 more)
INCI: DECYLAMINE OXIDE
Decylamine Oxide (CAS 2605-79-0) is a cosmetic cosmetic ingredient functioning as Antistatic, cleansing, foam boosting (surfactant). NOAEL 0.1 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 2605-79-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Decylamine Oxide is classified GHS Danger (H302, H315, H318, H400, H411) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antistatic, cleansing, foam boosting (surfactant)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
N,N-dimethyldecan-1-amine oxide
InChIKey
ZRKZFNZPJKEWPC-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not restricted under 21 CFR Parts 700–740
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Decylamine Oxide.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Decylamine Oxide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =100 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Decylamine Oxide across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Cleaning agent
Emulsifier
Foamant
Softener and conditioner
Solubility enhancer
Surfactant (surface active agent)
Wetting agent (non-aqueous)
Regulatory List Membership (1)
EPA Safer Chemical Ingredients List (SCIL)
Expert Verdict
Expert safety assessment and concern-level summary for Decylamine Oxide.
Regulatory Flags
potential-allergen
epa_safer_alternative
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Decylamine Oxide by CAS number or substance name.
Studies
1
Lowest NOAEL
100 mg/kg bw/day
Highest NOAEL
100 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Capric dimethyl amine oxide
1-Decanamine, N,N-dimethyl-, N-oxide
EINECS 220-020-5
UNII-G387VUT5EZ
Decyl dimethyl amine oxide
N,N-Dimethyl-1-decanamine-N-oxide
N,N-dimethyldecylamine N-oxide
decylamine-N,N-dimethyl-N-oxide
Chemical Function
Surfactant (surface active agent)
Solubility enhancer
Anti-static agent
Cleaning agent
Softener and conditioner
Wetting agent (non-aqueous)
Emulsifier
Regulatory Lists
SCIL (9/2019)
Canada; pharmaceutical
fracking; water
Australian Status
AICIS status: listed_with_terms
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the introduction volume of the chemical exceeds 1...
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1232157
Frequently Asked Questions
Is Decylamine Oxide allowed in the EU?
Decylamine Oxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Decylamine Oxide do in cosmetics?
Decylamine Oxide functions as: Antistatic, cleansing, foam boosting (surfactant). It is classified as a cosmetic ingredient in our database. CAS number: 2605-79-0.
What is the NOAEL for Decylamine Oxide?
The NOAEL (No Observed Adverse Effect Level) for Decylamine Oxide is =100 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is Decylamine Oxide used outside cosmetics?
Decylamine Oxide also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Decylamine Oxide have different safety status in cosmetics vs industrial chemicals?
Decylamine Oxide is classified GHS Danger (H302, H315, H318, H400, H411) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Decylamine Oxide compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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