NOAEL Data REACH Registered Cosmetic Ingredient

N,N-Dimethyldecylamine oxide

Also known as: Capric dimethyl amine oxide, 1-Decanamine, N,N-dimethyl-, N-oxide, EINECS 220-020-5, UNII-G387VUT5EZ, Decyl dimethyl amine oxide (+4 more)

CAS 2605-79-0

N,N-Dimethyldecylamine oxide (CAS 2605-79-0) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Decylamine Oxide →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
3
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 15 fields
Name
N,N-Dimethyldecylamine oxide
CAS Number
2605-79-0
DTXSID
DTXSID7042190
Molecular Formula
C12H27NO
InChI Key
ZRKZFNZPJKEWPC-UHFFFAOYSA-N
Monoisotopic Mass
201.209264
Synonyms
Capric dimethyl amine oxide1-Decanamine, N,N-dimethyl-, N-oxideEINECS 220-020-5UNII-G387VUT5EZDecyl dimethyl amine oxideDecylamine oxideN,N-Dimethyl-1-decanamine-N-oxideN,N-dimethyldecylamine N-oxidedecylamine-N,N-dimethyl-N-oxide

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 13 records
Surfactant (surface active agent)Solubility enhancerAnti-static agentCleaning agentSoftener and conditionerWetting agent (non-aqueous)EmulsifierFoamant

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
SCIL (9/2019)USEPASafer Chemical Ingredients List
Canada; pharmaceuticalDrugBankDrugBank
fracking; waterNY Department of ConservationCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
=6.2mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
G387VUT5EZUNIIFDA UNII substance identifier--openFDA substances
G387VUT5EZUNIIFDA UNII substance identifier--openFDA substances
G387VUT5EZUNIIFDA UNII substance identifier--openFDA substances
G387VUT5EZUNIIFDA UNII substance identifier--openFDA substances
-unitlessModel Score--NTP_ICE_endocrine
=100mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredN,N-dimethyldecylamine N-oxide220-020-5ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the introduction volume of the chemical exceeds 1 tonne per annum 2. A person who introduces this chemical must tell us in writing within 28 calendar days if they become aware of any of the following circumstances, namely, that since the assessment under the Industrial Chemicals (Notification and Assessment) Act 1989: a. the function or use of the chemical has changed, or is likely to change, significantly; b. the amount of the chemical being introduced has increased, or is likely to increase, significantly; c. in the case of a chemical not manufactured, or proposed to be manufactured, in Australia at the time of the assessment—it has begun to be manufactured in Australia; d. the method of manufacture of the chemical in Australia has changed, or is likely to change, in a way that may result in an increased risk of an adverse effect of the chemical on occupational health and safety, public health or the environment; e. additional information has become available to the person as to an adverse effect of the chemical on occupational health and safety, public health or the environment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL1232157
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for N,N-Dimethyldecylamine oxide?

N,N-Dimethyldecylamine oxide has 7 NOAEL studies in the database. The lowest reported value is 6.2 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include N,N-Dimethyldecylamine oxide?

N,N-Dimethyldecylamine oxide appears on 3 regulatory/inventory lists including SCIL (9/2019), Canada; pharmaceutical, fracking; water. Source: EPA CPDat.

Is N,N-Dimethyldecylamine oxide used in cosmetics?

Yes, N,N-Dimethyldecylamine oxide is also indexed as a cosmetic ingredient under the name Decylamine Oxide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for N,N-Dimethyldecylamine oxide come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Does N,N-Dimethyldecylamine oxide have different safety status in cosmetics vs industrial chemicals?

N,N-Dimethyldecylamine oxide is classified GHS Danger (H302, H315, H318, H400, H411) in the chemicals database but is allowed in EU cosmetics.

Is N,N-Dimethyldecylamine oxide used outside industrial chemicals?

N,N-Dimethyldecylamine oxide also appears in cosmetics, pharmaceutical databases.