Is Decapeptide-4 safe in cosmetics?
Decapeptide-4 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Decapeptide-4
INCI: DECAPEPTIDE-4
Decapeptide-4 (CAS 2227218-71-3 ; CosIng REF No: 84204) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent; mimics Somatomedin growth factor; promotes collagen. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 2227218-71-3 ; CosIng REF No: 84204 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent; mimics Somatomedin growth factor; promotes collagen production
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no CFR restriction; no FDA monograph
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Decapeptide-4.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
anti_pollution
{"cas_number": "223749-136-3", "ingredient_class": "other", "primary_mechanism": "barrier_reinforcement", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_kB_inhib…
Expert Verdict
Expert safety assessment and concern-level summary for Decapeptide-4.
Frequently Asked Questions
Is Decapeptide-4 allowed in the EU?
Decapeptide-4 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Decapeptide-4 do in cosmetics?
Decapeptide-4 functions as: Skin conditioning agent; mimics Somatomedin growth factor; promotes collagen production. It is classified as a cosmetic ingredient in our database. CAS number: 2227218-71-3 ; CosIng REF No: 84204.
Compliance Tools
Check Decapeptide-4 compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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