Is Cyclotetradecanone safe in cosmetics?
Cyclotetradecanone has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Cyclotetradecanone
Also known as: EINECS 222-758-3
INCI: CYCLOTETRADECANONE
Cyclotetradecanone (CAS 3603-99-4) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient (macrocyclic musk ketone). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 3603-99-4 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient (macrocyclic musk ketone)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
cyclotetradecanone
InChIKey
FUGDHQXYVPQGLJ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed. Permitted for use in cosmetics; no specific restrictions.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cyclotetradecanone.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Expert Verdict
Expert safety assessment and concern-level summary for Cyclotetradecanone.
Regulatory Flags
potential-allergen
fragrance-component
Known Synonyms
EINECS 222-758-3
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Cyclotetradecanone allowed in the EU?
Cyclotetradecanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cyclotetradecanone do in cosmetics?
Cyclotetradecanone functions as: Fragrance ingredient (macrocyclic musk ketone). It is classified as a cosmetic ingredient in our database. CAS number: 3603-99-4.
Is Cyclotetradecanone used outside cosmetics?
Cyclotetradecanone also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Cyclotetradecanone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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