Is Cyclopentadecanone safe in cosmetics?
Cyclopentadecanone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Cyclopentadecanone
INCI: CYCLOPENTADECANONE
Cyclopentadecanone (CAS Commonly cited CAS for cyclopentadecanone macrocyclic ketone (exact CAS varies by isomer; RIFM safety assessment exists)) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient (macrocyclic musk-type ketone). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Commonly cited CAS for cyclopentadecanone macrocyclic ketone (exact CAS varies by isomer; RIFM safety assessment exists)
View industrial chemical safety profile →
Function
Fragrance ingredient (macrocyclic musk-type ketone)
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA restriction; considered safe for use in fragrance with RIFM/CIR-type review.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cyclopentadecanone.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Cyclopentadecanone.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Cyclopentadecanone by CAS number or substance name.
Studies
6
Lowest NOAEL
100 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Frequently Asked Questions
Is Cyclopentadecanone allowed in the EU?
Cyclopentadecanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cyclopentadecanone do in cosmetics?
Cyclopentadecanone functions as: Fragrance ingredient (macrocyclic musk-type ketone). It is classified as a cosmetic ingredient in our database. CAS number: Commonly cited CAS for cyclopentadecanone macrocyclic ketone (exact CAS varies by isomer; RIFM safety assessment exists).
Compliance Tools
Check Cyclopentadecanone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Is Cyclopentadecanone in Your Products?
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Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Cyclopentadecanone in your formulation.