Is Cyanotis Arachnoidea Root Extract safe in cosmetics?
Cyanotis Arachnoidea Root Extract has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Cyanotis Arachnoidea Root Extract
Also known as: 20E, BRN 1917578, Commisterone, Crustecdyson, Crustecdysone (+14 more)
INCI: CYANOTIS ARACHNOIDEA ROOT EXTRACT
Cyanotis Arachnoidea Root Extract (CAS 5289-74-7) is a cosmetic cosmetic ingredient functioning as Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 5289-74-7 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
InChIKey
NKDFYOWSKOHCCO-YPVLXUMRSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No FDA monograph; no CIR report
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cyanotis Arachnoidea Root Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Cyanotis Arachnoidea Root Extract.
Regulatory Flags
data-sparse
no-sccs-opinion
no-cir-report
phytoecdysteroid
botanical-extract
Known Synonyms
20E
BRN 1917578
Commisterone
Crustecdyson
Crustecdysone
Ecdysteron
2-beta,3-beta,14,20,22,25-Hexahydroxy-5-beta-cholet-7-en-6-one
Isoinokosterone
Polypodine A
Viticosterone
NSC 629484
(+)-Ecdysterone
beta-Ecdisone
Polypodine C
Ekdisten
UNII-779A7KPL0Y
Ecdysterone
beta-Ecdysone
beta-Ecdysterone
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
20-HYDROXYECDYSONE
ChEMBL ID
CHEMBL224128
Max Phase
2
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Ecdysterone (Beta-Ecdysterone)
Food Category
sports_nutrition
Frequently Asked Questions
Is Cyanotis Arachnoidea Root Extract allowed in the EU?
Cyanotis Arachnoidea Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cyanotis Arachnoidea Root Extract do in cosmetics?
Cyanotis Arachnoidea Root Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 5289-74-7.
Is Cyanotis Arachnoidea Root Extract used outside cosmetics?
Cyanotis Arachnoidea Root Extract also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Not Reported
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