Coumaric Acid

Also known as: 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (2E)-, (2E)-3-(4-Hydroxyphenyl)acrylic acid, 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (E)-, Cinnamic acid, p-hydroxy-, (E)-, (2E)-3-(4-Hydroxyphenyl)prop-2-enoic acid (+14 more)

INCI: COUMARIC ACID

Coumaric Acid (CAS 501-98-4) is a cosmetic cosmetic ingredient functioning as antioxidant, skin conditioning, skin brightening. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 501-98-4 →

Auto-generated CPSR Part A draft with source citations
Function
antioxidant, skin conditioning, skin brightening
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C9H8O3
MW
164.16 g/mol
PubChem CID
637542
IUPAC Name
(E)-3-(4-hydroxyphenyl)prop-2-enoic acid
InChIKey
NGSWKAQJJWESNS-ZZXKWVIFSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not specifically restricted; used as cosmetic active under general safety provisions

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Coumaric Acid.

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Expert safety assessment and concern-level summary for Coumaric Acid.

Regulatory Flags

p-coumaric-acid tyrosinase-inhibitor skin-brightening antioxidant phenolic-acid natural

Known Synonyms

2-Propenoic acid, 3-(4-hydroxyphenyl)-, (2E)- (2E)-3-(4-Hydroxyphenyl)acrylic acid 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (E)- Cinnamic acid, p-hydroxy-, (E)- (2E)-3-(4-Hydroxyphenyl)prop-2-enoic acid (E)-3-(4-Hydroxyphenyl)-2-propenoic acid (E)-3-(4-Hydroxyphenyl)acrylic acid (E)-4-Hydroxycinnamic acid (E)-p-Coumaric acid (E)-p-Hydroxycinnamic acid Naringeninic acid p-Hydroxy-trans-cinnamic acid p-trans-Coumaric acid trans-3-(4-Hydroxyphenyl)-2-propenoic acid trans-4-Coumaric acid trans-4-Hydroxycinnamic acid trans-p-Coumaric acid trans-p-Coumarinic acid trans-p-Hydroxycinnamic acid

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
COUMARIC ACID
ChEMBL ID
CHEMBL66879
View full pharmaceutical profile →

Frequently Asked Questions

Is Coumaric Acid safe in cosmetics?

Coumaric Acid has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Coumaric Acid allowed in the EU?

Coumaric Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Coumaric Acid do in cosmetics?

Coumaric Acid functions as: antioxidant, skin conditioning, skin brightening. It is classified as a cosmetic ingredient in our database. CAS number: 501-98-4.

Is Coumaric Acid used outside cosmetics?

Coumaric Acid also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Coumaric Acid have different safety status in cosmetics vs industrial chemicals?

Coumaric Acid is classified GHS Danger (H301, H311, H314, H315, H317, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.

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