Is Cordyceps Extract safe in cosmetics?
Cordyceps Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Active Ingredient
Cordyceps Extract
Also known as: Peptones, Hydrolyzed protein, Proteins, peptones
INCI: CORDYCEPS SINENSIS EXTRACT
Cordyceps Extract (CAS 73049-73-7) is a cosmetic active ingredient functioning as Extract from Cordyceps sinensis (caterpillar fungus) mycelium. Active. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 73049-73-7 →
Auto-generated CPSR Part A draft with source citations
Function
Extract from Cordyceps sinensis (caterpillar fungus) mycelium. Active constituents: cordycepin (3'-deoxyadenosine, antioxidant and anti-inflammatory), beta-glucans (barrier/immunomodulatory), adenosine, and polysaccharides. Mechanisms: antioxidant via cordycepin free-radical scavenging; anti-inflammatory via inhibition of pro-inflammatory cytokine production; beta-glucan barrier support; claimed adaptogenic anti-stress activity.
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted without restriction. Patent activity (CN115444928A) indicates industry R&D investment in peptide-mushroom combinations. Adaptogenic topical claims require stronger peer-reviewed validation. Antioxidant and anti-inflammatory activity better-evidenced. MoCRA safety substantiation required.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cordyceps Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CA | restricted | No concentration limit | All cosmetics |
Additional Ingredient Properties
5 property records from structured ingredient metadata.
acne
{"anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_acne": "No restriction", "c…
anti_pollution
{"cas_number": "73-48-3", "ingredient_class": "antioxidant_pollution_shield", "primary_mechanism": "free_radical_scavenging", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation"…
fermentation
{"cas_number": "proprietary", "ingredient_class": "ferment_extract", "production_organism": "fungi", "fermentation_type": "submerged", "substrate_feedstock": "glucose, wood substrates", "bioactive_compounds_produced": "polysaccharides", "mechanism_of_action_skin": "immune modulation, hydration, antioxidant", "skin_benefit_primary": "moisturizing", "skin_benefit_secondary": "anti_aging, moisturizin…
self_tanning
{"cas_number": "73-03-0", "ingredient_class": "tan_accelerator", "tanning_mechanism": "melanin_stimulation", "color_development_onset_hours": "0.0", "full_color_development_hours": "0", "color_duration_days": "0", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "0", "pH_dependent_color": "no", "formaldehyde_release_concern": "no", "formaldehyde_release_ppm": "0", "AGE_…
uv_stability
{"uv_stable": "yes", "uv_degradation_rate": "stable", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "0", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_under_uv": …
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Film former
Flavouring and nutrient
Humectant
Softener and conditioner
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Cordyceps Extract.
Regulatory Flags
adaptogen
mushroom-extract
antioxidant
anti-inflammatory
beta-glucan
holistic-beauty
patent-cited
claims-substantiation-required
fda_food_additive
Known Synonyms
Peptones
Hydrolyzed protein
Proteins, peptones
Chemical Function
Humectant
Softener and conditioner
Film former
Anti-static agent
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Cordyceps Extract allowed in the EU?
Cordyceps Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cordyceps Extract do in cosmetics?
Cordyceps Extract functions as: Extract from Cordyceps sinensis (caterpillar fungus) mycelium. Active constituents: cordycepin (3'-deoxyadenosine, antioxidant and anti-inflammatory), beta-glucans (barrier/immunomodulatory), adenosine, and polysaccharides. Mechanisms: antioxidant via cordycepin free-radical scavenging; anti-inflammatory via inhibition of pro-inflammatory cytokine production; beta-glucan barrier support; claimed adaptogenic anti-stress activity.. It is classified as a Active Ingredient in our database. CAS number: 73049-73-7.
Compliance Tools
Check Cordyceps Extract compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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