Is Cloflucarban safe in cosmetics?
Cloflucarban has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
Poor
Cosmetic Ingredient
Cloflucarban
Also known as: Halocarban, Cloflucarbon, 4,4'-Dichloro-3-(trifluoromethyl)carbanilide, EINECS 206-724-5, NSC 114133 (+7 more)
INCI: CLOFLUCARBAN
Cloflucarban (CAS 369-77-7) is a cosmetic cosmetic ingredient functioning as Antimicrobial, Deodorant. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 369-77-7 →
Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial, Deodorant
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
1-(4-chlorophenyl)-3-[4-chloro-3-(trifluoromethyl)phenyl]urea
InChIKey
ZFSXZJXLKAJIGS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not GRAS. Listed under 21 CFR 310.545 as lacking adequate data for general recognition of safety and effectiveness. Banned in consumer antiseptic hand wash and body wash products as of September 6, 2017.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cloflucarban.
Calculate MoS for your specific formulation with the MoS Calculator.
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (2)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | permitted_preservative | 0.2 | Rinse-off products |
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Deodorizer
Expert Verdict
Expert safety assessment and concern-level summary for Cloflucarban.
Known Synonyms
Halocarban
Cloflucarbon
4,4'-Dichloro-3-(trifluoromethyl)carbanilide
EINECS 206-724-5
NSC 114133
Trifluoromethyldichlorocarbanilide
3-Trifluoromethyl-4,4'-dichloro-N,N'-diphenylurea
Irgasan CF3
1-(4-Chlorphenyl)-3-(4-chlor-3-trifluormethylphenyl)urea
Halocarbano
Halocarbanum
UNII-I5ZZY3DC5G
Chemical Function
Biocide
Deodorizer
Regulatory Lists
pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
CLOFLUCARBAN
ChEMBL ID
CHEMBL1981438
Max Phase
2
Frequently Asked Questions
Is Cloflucarban allowed in the EU?
Cloflucarban EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Cloflucarban do in cosmetics?
Cloflucarban functions as: Antimicrobial, Deodorant. It is classified as a cosmetic ingredient in our database. CAS number: 369-77-7.
Is Cloflucarban used outside cosmetics?
Cloflucarban also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Cloflucarban compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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