Is Citronellyl Propionate safe in cosmetics?
Citronellyl Propionate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Citronellyl Propionate
Also known as: Citronellyl propanoate, 3,7-Dimethyl-6-octen-1-ol propanoate, 3,7-Dimethyl-6-octen-1-yl propanoate, 3,7-Dimethyl-6-octen-1-yl propionate, EINECS 205-461-3 (+5 more)
INCI: CITRONELLYL PROPIONATE
Citronellyl Propionate (CAS 141-14-0) is a cosmetic cosmetic ingredient functioning as Fragrance / Perfuming agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 141-14-0 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance / Perfuming agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3,7-dimethyloct-6-enyl propanoate
InChIKey
POPNTVRHTZDEBW-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not separately reviewed by CIR; deferred to RIFM. FEMA GRAS for food
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Citronellyl Propionate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2592 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
61
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
CITRONELLYL PROPIONATE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 40-JECFA 49/329 (1997)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Citronellyl Propionate.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
Citronellyl propanoate
3,7-Dimethyl-6-octen-1-ol propanoate
3,7-Dimethyl-6-octen-1-yl propanoate
3,7-Dimethyl-6-octen-1-yl propionate
EINECS 205-461-3
EINECS 278-466-1
FEMA No. 2316
6-Octen-1-ol, 3,7-dimethyl-, propionate
Propionic acid, ester with citronellol
UNII-87R1092U7J
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3185956
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
CITRONELLYL PROPIONATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Citronellyl Propionate allowed in the EU?
Citronellyl Propionate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Citronellyl Propionate do in cosmetics?
Citronellyl Propionate functions as: Fragrance / Perfuming agent. It is classified as a cosmetic ingredient in our database. CAS number: 141-14-0.
Is Citronellyl Propionate used outside cosmetics?
Citronellyl Propionate also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Citronellyl Propionate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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