Is CI 75470 (Carmine) safe in cosmetics?
CI 75470 (Carmine) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
CI 75470 (Carmine)
Also known as: B Rose liquid, Carmine (Coccus cacti L.), Cochineal (Coccus cacti L.), Cochineal extract lake, EINECS 215-724-4 (+8 more)
INCI: CI 75470
CI 75470 (Carmine) (CAS 1390-65-4) is a cosmetic cosmetic ingredient functioning as Colorant. Natural red pigment derived from the dried bodies of female cochineal. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 1390-65-4 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant. Natural red pigment derived from the dried bodies of female cochineal insects (Dactylopius coccus Costa); also known as Carmine, Cochineal, Crimson Lake, Carmine Lake, Natural Red 4, and food colorant E120. The active chromophore is carminic acid precipitated with aluminium or calcium salts. Imparts bright red-pink coloration to cosmetic products including lipsticks, eyeshadows, and blushes. The only organic red/pink colorant approved for eye area use in the US. Purity criteria per Commission Directive 95/45/EC.
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA permanently lists Carmine as a color additive exempt from certification under 21 CFR 73.2087 for cosmetics generally including eye area use, and under 21 CFR 73.1087 for ingested and externally applied drugs. Also approved for food use (21 CFR 73.100). As of 2011, all products containing carmine must declare it by name on the label. Carmine is the only organic pink/red colorant permitted for use around the eye area in the US.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 75470 (Carmine).
Calculate MoS for your specific formulation with the MoS Calculator.
EPA ToxValDB — Toxicity Values
2 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| LD50 | >2000 mg/kg | Rat | oral | - | ECHA IUCLID |
| ADI | <=5 mg/kg | Human | oral | - | WHO JECFA ADI |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE; GROUP
SVHC Candidate
No
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (4)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | permitted_colorant | - | All cosmetics (Class 1) |
| GCC | halal_restricted | - | All cosmetics |
| BR | permitted_colorant | - | Column 1: All products |
| ASEAN | permitted_colorant | - | All products |
Additional Ingredient Properties
1 property record from structured ingredient metadata.
colorant
{"Common_Name": "Cochineal Extract", "Chemical_Name": "Carminic acid", "CAS_Number": "1390-65-4", "Colorant_Type": "Natural Colorant", "Approved_Uses": "All cosmetics", "Max_Concentration_%": "No limit", "EU_Status": "Approved", "US_FDA_Status": "Approved", "Notes": "Red from insects"}
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Dye
Flavouring and nutrient
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for CI 75470 (Carmine).
Regulatory Flags
natural-colorant
insect-derived
eu-annex-iv
fda-exempt-certification
eye-area-permitted
allergen-risk
ige-mediated
mandatory-label-declaration
vegan-concern
e120
anaphylaxis-risk
fda_food_additive
Known Synonyms
B Rose liquid
Carmine (Coccus cacti L.)
Cochineal (Coccus cacti L.)
Cochineal extract lake
EINECS 215-724-4
FEMA No. 2242
FEMA No. 2330
Carmine aluminum lake
Carmine red
CC 1000WS
CCRIS 1204
215-724-4
EC No.: 215-724-4
Chemical Function
Deodorizer
Dye
Flavouring and nutrient
Regulatory Lists
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is CI 75470 (Carmine) allowed in the EU?
CI 75470 (Carmine) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 75470 (Carmine) do in cosmetics?
CI 75470 (Carmine) functions as: Colorant. Natural red pigment derived from the dried bodies of female cochineal insects (Dactylopius coccus Costa); also known as Carmine, Cochineal, Crimson Lake, Carmine Lake, Natural Red 4, and food colorant E120. The active chromophore is carminic acid precipitated with aluminium or calcium salts. Imparts bright red-pink coloration to cosmetic products including lipsticks, eyeshadows, and blushes. The only organic red/pink colorant approved for eye area use in the US. Purity criteria per Commission Directive 95/45/EC.. It is classified as a cosmetic ingredient in our database. CAS number: 1390-65-4.
Is CI 75470 (Carmine) used outside cosmetics?
CI 75470 (Carmine) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CI 75470 (Carmine) compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Good
Similar safety
Antioxidant
Carmine
Moderate
Chemical family
colorant
Carmine (CI 75470)
Good
Chemical family
Deodorizer; Dye; Flavouring and nutrient
Cochineal (CI 75470 / Carmine)
Good
Chemical family
Colorant, masking agent
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