Is CI 75135 (Rubixanthin) safe in cosmetics?
CI 75135 (Rubixanthin) has a safety rating of "GOOD" in our database. EU status: permitted. US status: restricted.
Good
Cosmetic Ingredient
CI 75135 (Rubixanthin)
Also known as: beta-4-Caroten-3-ol, (3R)-, Rubixanthin, Natural yellow 27
INCI: CI 75135
CI 75135 (Rubixanthin) (CAS 3763-55-1) is a cosmetic cosmetic ingredient functioning as Colorant. Natural xanthophyll carotenoid pigment; also known as Rubixanthin,. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in food safety data.
View industrial chemical safety profile for CAS 3763-55-1 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant. Natural xanthophyll carotenoid pigment; also known as Rubixanthin, beta,tau-Caroten-3-ol, (3R)-beta-4-Caroten-3-ol, and Natural Yellow 27. Found naturally in rose hips (Rosa canina). Imparts red-orange to yellow coloration to cosmetic products. Retains Annex IV status for cosmetics.
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E,19E)-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,23-undecaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol
InChIKey
ABTRFGSPYXCGMR-AXXBKCDFSA-N
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
Rubixanthin (CAS 3763-55-1) is not listed in FDA 21 CFR Parts 73 or 74 as an approved color additive for cosmetics or drugs. No FDA color additive petition has been approved for cosmetic use. Use as a declared cosmetic colorant is not formally authorized under US color additive regulations; may be considered for use as a functional ingredient but regulatory status as a color additive is unsupported.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 75135 (Rubixanthin).
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: Yellow
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (IV - Colorants)
BRIN Brazil/India Cosmetics
India: Permitted Colorant
Additional Ingredient Properties
1 property record from structured ingredient metadata.
colorant
{"Common_Name": "Lycopene", "Chemical_Name": "Lycopene", "CAS_Number": "502-65-8", "Colorant_Type": "Natural Colorant", "Approved_Uses": "All cosmetics", "Max_Concentration_%": "No limit", "EU_Status": "Approved", "US_FDA_Status": "Approved", "Notes": "Red from tomatoes"}
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Expert Verdict
Expert safety assessment and concern-level summary for CI 75135 (Rubixanthin).
Regulatory Flags
natural-colorant
carotenoid
xanthophyll
eu-annex-iv
rose-hip-derived
oil-soluble
not-fda-listed
e161d-withdrawn-food
low-concern
Known Synonyms
beta-4-Caroten-3-ol, (3R)-
Rubixanthin
Natural yellow 27
Chemical Function
Dye
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Rubixanthin
E Number
E161d
Food Category
colorant
Frequently Asked Questions
Is CI 75135 (Rubixanthin) allowed in the EU?
CI 75135 (Rubixanthin) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 75135 (Rubixanthin) do in cosmetics?
CI 75135 (Rubixanthin) functions as: Colorant. Natural xanthophyll carotenoid pigment; also known as Rubixanthin, beta,tau-Caroten-3-ol, (3R)-beta-4-Caroten-3-ol, and Natural Yellow 27. Found naturally in rose hips (Rosa canina). Imparts red-orange to yellow coloration to cosmetic products. Retains Annex IV status for cosmetics.. It is classified as a cosmetic ingredient in our database. CAS number: 3763-55-1.
Is CI 75135 (Rubixanthin) used outside cosmetics?
CI 75135 (Rubixanthin) also appears in food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CI 75135 (Rubixanthin) compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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