Is CI 58000 safe in cosmetics?
CI 58000 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
Moderate
Cosmetic Ingredient
CI 58000
Also known as: C.I. 58000C, D and C Orange No. 15, D and C Orange Number 15D, 4-08-00-03256, C.I. Mordant Red 11C (+15 more)
CI 58000 (CAS 72-48-0) is a cosmetic cosmetic ingredient functioning as Colorant. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 72-48-0 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
1,2-dihydroxyanthracene-9,10-dione
InChIKey
RGCKGOZRHPZPFP-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
restricted
US Notes
Not listed as an FDA-certified color additive for cosmetics in the US. EU-permitted with restriction. Prohibited in hair dye products. EU Annex IV/86, Annex II/1361.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 58000.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
Ceased manufacture
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1361
(EC) 2013/344
Annex IV — Permitted Colorants
Product type: Red
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
India: Permitted Colorant
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (3)
EU Banned in Cosmetics
EU Regulated in Personal Care
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for CI 58000.
Regulatory Flags
not-for-hair-dye
not-fda-approved
anthraquinone
possible-sensitizer
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
C.I. 58000C
D and C Orange No. 15
D and C Orange Number 15D
4-08-00-03256
C.I. Mordant Red 11C
C.I. Pigment Red 83
C.I. Pigment Red 83C
Alizarine paste 20% bluish
Alizarinprimeveroside
Alizerine NAC
Alizerine Red IPP
BRN 1914037
Certiqual Alizarine D
Deep Crimson Madder 10821E
EINECS 200-782-5
Eljon Madder M
Mitsui Alizarine BS
Sanyo Carmine L2B
Turkey Red W
UNII-60MEW57T9G
Chemical Function
Dye
Regulatory Lists
Europe; Personal care
banned; Europe; Personal care
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ATHRAQUINONES A
ChEMBL ID
CHEMBL55814
Frequently Asked Questions
Is CI 58000 allowed in the EU?
CI 58000 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 58000 do in cosmetics?
CI 58000 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 72-48-0.
Is CI 58000 used outside cosmetics?
CI 58000 also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CI 58000 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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