Is CI 49000 safe in cosmetics?
CI 49000 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
Moderate
Cosmetic Ingredient
CI 49000
Also known as: Direct Yellow 59
CI 49000 (CAS 8064-60-6) is a cosmetic cosmetic ingredient functioning as Colorant. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 8064-60-6 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
sodium 2-[2-(4-aminophenyl)-1,3-benzothiazol-6-yl]-6-methyl-1,3-benzothiazole-7-sulfonate
InChIKey
RSRNHSYYBLEMOI-UHFFFAOYSA-M
Regulatory Status
EU EU Status
restricted
US US Status
restricted
US Notes
Not listed as an approved FDA D&C or FD&C color additive for cosmetics in the US. Not confirmed in EU Annex IV positive list for cosmetic use; primarily a laboratory fluorescent dye (Primuline / Direct Yellow 59) with limited cosmetic application.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 49000.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for CI 49000.
Regulatory Flags
not-fda-approved
not-confirmed-eu-annex-iv
synthetic-dye
thiazole-dye
primarily-laboratory-use
primuline
direct-yellow-59
Known Synonyms
Direct Yellow 59
Frequently Asked Questions
Is CI 49000 allowed in the EU?
CI 49000 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 49000 do in cosmetics?
CI 49000 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 8064-60-6.
Compliance Tools
Check CI 49000 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
CI 40800 (Beta-Carotene)
Excellent
Same category
Colorant. Synthetic or naturally deri...
CI 75130 (Beta-Carotene)
Excellent
Same category
Colorant. Synthetic or plant-derived ...
CI 75170 (Guanine)
Excellent
Same category
Colorant. Natural crystalline materia...
CI 77004 (Kaolin)
Excellent
Same category
Colorant. Natural white clay mineral ...
CI 77007 (Ultramarine Blue)
Excellent
Same category
Colorant. Inorganic mineral pigment s...
CI 77019 (Mica)
Excellent
Same category
Colorant; Opacifying Agent; Bulking A...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
CI 10006
Moderate
Browse nearby
Colorant (green)
CI 10020
Moderate
Browse nearby
Colorant (green)
CI 10316 (Ext. D&C Yellow No. 7)
Moderate
Browse nearby
Colorant. Synthetic nitro dye (Disodi...
Is CI 49000 in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for CI 49000 in your formulation.