Is CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) safe in cosmetics?
CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) has a safety rating of "GOOD" in our database. EU status: permitted. US status: prohibited.
Good
Cosmetic Ingredient
CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid)
Also known as: Food orange 7
INCI: CI 40825
CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) (CAS 1109-11-1) is a cosmetic cosmetic ingredient functioning as Colorant. Synthetic carotenoid colorant (Ethyl 8'-Apo-Beta-Caroten-8'-oate,. EU Regulation 1223/2009 status: permitted, max Listed in Annex IV of EU Cosmetics Regulation (EC) No. 1223/2009 (Entry IV/57). Permitted as a colorant in all cosmetic products without a specified maximum concentration. Purity criteria must comply with Commission Directive 95/45/EC as applicable to E160f.. Industrial safety data is also available in the chemical safety database. Same-CAS public records
View industrial chemical safety profile for CAS 1109-11-1 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant. Synthetic carotenoid colorant (Ethyl 8'-Apo-Beta-Caroten-8'-oate, also known as Beta-Apo-8'-Carotenic Acid Ethyl Ester and E160f). Imparts orange-to-red coloration to cosmetic products. A synthetic ester of the carotenoid acid derived from beta-carotene cleavage. Structurally related to apocarotenal (CI 40820) and beta-carotene (CI 40800). Used as a colorant in all cosmetic product types permitted under EU Annex IV.
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
ethyl (2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-tetramethyl-17-(2,6,6-trimethylcyclohexen-1-yl)heptadeca-2,4,6,8,10,12,14,16-octaenoate
InChIKey
GIRXTOSJOKKBHO-BQTUIHPCSA-N
Regulatory Status
EU EU Status
permitted
EU Max Conc.
Listed in Annex IV of EU Cosmetics Regulation (EC) No. 1223/2009 (Entry IV/57). Permitted as a colorant in all cosmetic products without a specified maximum concentration. Purity criteria must comply with Commission Directive 95/45/EC as applicable to E160f.
US US Status
prohibited
US Notes
Not listed as an FDA-certified or exempt color additive for cosmetics under 21 CFR Parts 73, 74, or 82. CI 40825 (beta-apo-8'-carotenic acid ethyl ester / E160f) does not appear on the FDA Color Additives Permitted for Use in Cosmetics list. Regulatory status for US cosmetic use is not established; formulators must confirm permissibility before US market distribution.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid).
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: Orange
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (IV - Colorants)
BRIN Brazil/India Cosmetics
India: Permitted Colorant
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Expert Verdict
Expert safety assessment and concern-level summary for CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid).
Regulatory Flags
eu-annex-iv
not-fda-listed
all-cosmetics-eu
carotenoid-ester
food-additive-e160f
no-concentration-limit-eu
us-regulatory-gap
purity-criteria-required
synthetic-carotenoid
Known Synonyms
Food orange 7
Chemical Function
Dye
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Ethyl ester of beta-apo-8'-carotenic acid
E Number
E160f
Food Category
colorant
Frequently Asked Questions
Is CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) allowed in the EU?
CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) EU regulatory status: permitted. Maximum allowed concentration: Listed in Annex IV of EU Cosmetics Regulation (EC) No. 1223/2009 (Entry IV/57). Permitted as a colorant in all cosmetic products without a specified maximum concentration. Purity criteria must comply with Commission Directive 95/45/EC as applicable to E160f.. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) do in cosmetics?
CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) functions as: Colorant. Synthetic carotenoid colorant (Ethyl 8'-Apo-Beta-Caroten-8'-oate, also known as Beta-Apo-8'-Carotenic Acid Ethyl Ester and E160f). Imparts orange-to-red coloration to cosmetic products. A synthetic ester of the carotenoid acid derived from beta-carotene cleavage. Structurally related to apocarotenal (CI 40820) and beta-carotene (CI 40800). Used as a colorant in all cosmetic product types permitted under EU Annex IV.. It is classified as a cosmetic ingredient in our database. CAS number: 1109-11-1.
Is CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) used outside cosmetics?
CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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