Is CI 40215 safe in cosmetics?
CI 40215 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: prohibited.
Moderate
Cosmetic Ingredient
CI 40215
CI 40215 (CAS 1325-54-8) is a cosmetic cosmetic ingredient functioning as Colorant. NOAEL 300 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 1325-54-8 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
US US Status
prohibited
US Notes
Not listed as FDA-certified color additive for US cosmetics; not in 21 CFR Part 74 or 82
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 40215.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for CI 40215 across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: Orange
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (IV - Colorants)
Product type: Rinse-off products.
BRIN Brazil/India Cosmetics
India: Permitted Colorant
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Expert Verdict
Expert safety assessment and concern-level summary for CI 40215.
Regulatory Flags
direct-dye
eu-annex-iv-restricted
rinse-off-only
not-fda-approved
direct-orange-39
Chemical Function
Dye
Australian Status
AICIS status: listed
Frequently Asked Questions
Is CI 40215 allowed in the EU?
CI 40215 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 40215 do in cosmetics?
CI 40215 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 1325-54-8.
Is CI 40215 used outside cosmetics?
CI 40215 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CI 40215 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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