Is CI 20040 (Pigment Yellow 16) safe in cosmetics?
CI 20040 (Pigment Yellow 16) has a safety rating of "GOOD" in our database. EU status: restricted. US status: prohibited.
Good
Cosmetic Ingredient
CI 20040 (Pigment Yellow 16)
Also known as: Butanamide, N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[2-(2,4-dichlorophenyl)diazenyl]-3-oxo-, N,N'-(3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2-((2,4-dichlorophenyl)azo)-3-oxobutyramide), Butanamide, N,N'-(3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2-((2,4-dichlorophenyl)azo)-3-oxo-, Chromatex Yellow JN, EINECS 227-783-3 (+15 more)
INCI: CI 20040
CI 20040 (Pigment Yellow 16) (CAS 5979-28-2) is a cosmetic cosmetic ingredient functioning as Colorant. Synthetic bis-azo yellow pigment (N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4. EU Regulation 1223/2009 status: restricted, max Annex IV listed; permitted as colorant exclusively in rinse-off cosmetics; no maximum concentration specified. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 5979-28-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
CI 20040 (Pigment Yellow 16) is classified GHS Danger (H350) in the chemicals database but is restricted in EU cosmetics at max Annex IV listed; permitted as colorant exclusively in rinse-off cosmetics; no maximum concentration specified.
Source: Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Colorant. Synthetic bis-azo yellow pigment (N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide]), also known as Pigment Yellow 16 and Permanent Yellow NCG. Imparts yellow coloration to cosmetic products. Insoluble pigment used as surface colorant in rinse-off cosmetics only. Organic azo pigment containing a dichlorobiphenyl core. Not an oxidative hair dye.
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-[(2,4-dichlorophenyl)diazenyl]-N-[4-[4-[[2-[(2,4-dichlorophenyl)diazenyl]-3-oxobutanoyl]amino]-3-methylphenyl]-2-methylphenyl]-3-oxobutanamide
InChIKey
JFMYRCRXYIIGBB-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
EU Max Conc.
Annex IV listed; permitted as colorant exclusively in rinse-off cosmetics; no maximum concentration specified
US US Status
prohibited
US Notes
Not listed as an FDA-certified or exempt color additive for cosmetics under 21 CFR. Pigment Yellow 16 does not appear on the FDA Color Additives Permitted for Use in Cosmetics list. Use in US cosmetics is not explicitly authorized; formulators should verify status prior to marketing.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 20040 (Pigment Yellow 16).
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: Yellow
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (IV - Colorants)
Product type: Rinse-off products.
BRIN Brazil/India Cosmetics
India: Permitted Colorant
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Regulated in Personal Care
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for CI 20040 (Pigment Yellow 16).
Regulatory Flags
synthetic-colorant
azo-dye
pigment
eu-annex-iv
rinse-off-only
not-fda-listed
insoluble-pigment
biphenyl-core
eu_cosing_listed
Known Synonyms
Butanamide, N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[2-(2,4-dichlorophenyl)diazenyl]-3-oxo-
N,N'-(3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2-((2,4-dichlorophenyl)azo)-3-oxobutyramide)
Butanamide, N,N'-(3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2-((2,4-dichlorophenyl)azo)-3-oxo-
Chromatex Yellow JN
EINECS 227-783-3
Helio Fast Yellow FPV
Hostaperm Yellow NCG
Irgalite Fast Yellow GC
Light Yellow JN
NSC 521238
Permanent Yellow NCG
Pigment Fast Yellow 3GL
Pigment Yellow 16
Pigment Yellow 3GL
Plastol Yellow 3GL
PV-Yellow G
Resamine Fast Yellow 3GL
Segnale Light Yellow NCG
Siloton Yellow NCG
Termosolido Yellow GL Supra
Chemical Function
Dye
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is CI 20040 (Pigment Yellow 16) allowed in the EU?
CI 20040 (Pigment Yellow 16) EU regulatory status: restricted. Maximum allowed concentration: Annex IV listed; permitted as colorant exclusively in rinse-off cosmetics; no maximum concentration specified. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 20040 (Pigment Yellow 16) do in cosmetics?
CI 20040 (Pigment Yellow 16) functions as: Colorant. Synthetic bis-azo yellow pigment (N,N'-(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[(2,4-dichlorophenyl)azo]-3-oxobutyramide]), also known as Pigment Yellow 16 and Permanent Yellow NCG. Imparts yellow coloration to cosmetic products. Insoluble pigment used as surface colorant in rinse-off cosmetics only. Organic azo pigment containing a dichlorobiphenyl core. Not an oxidative hair dye.. It is classified as a cosmetic ingredient in our database. CAS number: 5979-28-2.
Is CI 20040 (Pigment Yellow 16) used outside cosmetics?
CI 20040 (Pigment Yellow 16) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does CI 20040 (Pigment Yellow 16) have different safety status in cosmetics vs industrial chemicals?
CI 20040 (Pigment Yellow 16) is classified GHS Danger (H350) in the chemicals database but is restricted in EU cosmetics at max Annex IV listed; permitted as colorant exclusively in rinse-off cosmetics; no maximum concentration specified.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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