Is Chlorotrifluoropropene safe in cosmetics?
Chlorotrifluoropropene has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Chlorotrifluoropropene
Chlorotrifluoropropene (CAS 102687-65-0 (trans-1-Chloro-3,3,3-trifluoropropene / HFO-1233zd)) is classified as a cosmetic ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
102687-65-0 (trans-1-Chloro-3,3,3-trifluoropropene / HFO-1233zd)
View industrial chemical safety profile →
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CFCs are prohibited (21 CFR 700.23), but HFO-1233zd is not a CFC — it is an HFO (hydrofluoroolefin) with ultra-low GWP; not specifically restricted by FDA for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Chlorotrifluoropropene.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Chlorotrifluoropropene.
Frequently Asked Questions
Is Chlorotrifluoropropene allowed in the EU?
Chlorotrifluoropropene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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