Chamomile Extract (Matricaria Chamomilla Extract) (CAS 84082-60-0) is a cosmetic preservative functioning as Preservative. Reported NOAEL =200 mg/kg/d in rat (CIR_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
For full compliance data across multiple jurisdictions, use the
Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Chamomile Extract (Matricaria Chamomilla Extract).
Calculate MoS for your specific formulation with the
MoS Calculator.
Toxicological Studies
4 study endpoints found for Chamomile Extract (Matricaria Chamomilla Extract). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
Endpoint
Value
Route
Species
Study Type
Source
NOAEL
=200 mg/kg/d
oral
rat
oral toxicity
CIR_vision_codex
NOAEL
=200 mg/kg/d
oral
rat
oral toxicity
CIR_vision_codex
NOAEL
=200 mg/kg/d
oral
rat
oral toxicity
CIR_vision_codex
NOAEL
=200 mg/kg/d
oral
rat
oral toxicity
CIR_vision_codex
Sensitization Profile
Contact sensitization data for Chamomile Extract (Matricaria Chamomilla Extract) based on clinical patch test studies and IFRA standards.
Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
compositae-group
Reaction Type
contact-dermatitis
Source: IVDK; literature review
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
Public NOAEL study rows linked to Chamomile Extract (Matricaria Chamomilla Extract) by CAS number or substance name.
Studies
4
Lowest NOAEL
200 mg/kg/d
Highest NOAEL
200 mg/kg/d
CIR_vision_codex
Chemical Function
DeodorizerSoftener and conditionerFragrance
Regulatory Lists
children; Europe; Personal carechildren; Europe; Personal care - hair styling and care - shampoochildren; Europe; Personal care - specialized bath products - bubble bathchildren; Europe; Personal care - dental care - toothpasteEurope; Personal care - hair styling and care - shampoo-dandruffEurope; Personal careEurope; Personal careEurope; Personal careEurope; Personal careEurope; Personal careEurope; Personal careEurope; Personal careEurope; Personal careEurope; Personal careEurope; Personal care
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCEChEMBL / DrugCentral / FAERSDB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Is Chamomile Extract (Matricaria Chamomilla Extract) safe in cosmetics?
Chamomile Extract (Matricaria Chamomilla Extract) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 4 toxicological study endpoint(s) are available in our database.
Is Chamomile Extract (Matricaria Chamomilla Extract) allowed in the EU?
Chamomile Extract (Matricaria Chamomilla Extract) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Chamomile Extract (Matricaria Chamomilla Extract) do in cosmetics?
Chamomile Extract (Matricaria Chamomilla Extract) functions as: Preservative. It is classified as a Preservative in our database. CAS number: 84082-60-0.
What is the NOAEL for Chamomile Extract (Matricaria Chamomilla Extract)?
The NOAEL (No Observed Adverse Effect Level) for Chamomile Extract (Matricaria Chamomilla Extract) is =200 mg/kg/d based on a oral toxicity study via oral route in rat. A total of 4 study endpoints are available. Source: CIR_vision_codex.
Is Chamomile Extract (Matricaria Chamomilla Extract) used outside cosmetics?
Chamomile Extract (Matricaria Chamomilla Extract) also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Chamomile Extract (Matricaria Chamomilla Extract) compliance across multiple jurisdictions:
Is Chamomile Extract (Matricaria Chamomilla Extract) in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Chamomile Extract (Matricaria Chamomilla Extract) in your formulation.