Is Ceramide NG safe in cosmetics?
Ceramide NG has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Ceramide NG
Also known as: Ceramides, N-Acylsphingosine, N-Acylsphingosines, Synthetic ceramide, Synthetic ceramides (+1 more)
INCI: CERAMIDE NG
Ceramide NG (CAS 100403-19-8) is a cosmetic cosmetic ingredient functioning as Hair Conditioning, Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 100403-19-8 →
Auto-generated CPSR Part A draft with source citations
Function
Hair Conditioning, Skin Conditioning
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted; approximately 110 VCRP uses (as Ceramide 2, 2014); max concentration 0.2%
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ceramide NG.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
4 property records from structured ingredient metadata.
anti_pollution
{"cas_number": "100403-19-8", "ingredient_class": "other", "primary_mechanism": "barrier_reinforcement", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_kB_inhibi…
concentration
{"min_concentration_pct": "0.1", "max_concentration_pct": "3.0", "typical_concentration_pct": "1.0", "product_type": "Moisturizer", "function_at_concentration": "Barrier repair", "source": "Supplier TDS"}
cost_pricing
{"cost_tier": "premium", "estimated_cost_per_kg_usd_low": "420", "estimated_cost_per_kg_usd_high": "800", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "medium", "primary_source_region": "Japan", "bulk_discount_threshold_kg": "5", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Ceramide NP, C…
synergy
{"inci_name_2": "Ceramide AS", "synergy_type": "efficacy-boost", "synergy_description": "Non-hydroxy ceramides for barrier diversity", "combined_benefit": "Enhanced barrier structure, improved lipid diversity, better organization", "efficacy_multiplier": "1.8x", "mechanism_of_action": "Multiple ceramide types replicate natural SC lipid diversity for optimal barrier", "optimal_ratio": "1:1 (1.5% ea…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Softener and conditioner
Regulatory List Membership (2)
EU Regulated in Personal Care
EU Regulated in Personal Care
Expert Verdict
Expert safety assessment and concern-level summary for Ceramide NG.
Known Synonyms
Ceramides
N-Acylsphingosine
N-Acylsphingosines
Synthetic ceramide
Synthetic ceramides
EC No.: 309-560-3
Chemical Function
Softener and conditioner
Humectant
Regulatory Lists
Europe; Personal care
Europe; Personal care
Canada; Personal care; Substances in PCP - Canada (4/2014)
Frequently Asked Questions
Is Ceramide NG allowed in the EU?
Ceramide NG EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ceramide NG do in cosmetics?
Ceramide NG functions as: Hair Conditioning, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 100403-19-8.
Compliance Tools
Check Ceramide NG compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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