Is Centella Asiatica Extract safe in cosmetics?
Centella Asiatica Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Active Ingredient
Centella Asiatica Extract
Also known as: gotu kola
INCI: CENTELLA ASIATICA EXTRACT
Centella Asiatica Extract (CAS 84696-21-9) is a cosmetic active ingredient functioning as active, wound-healing, anti-inflammatory, collagen-stimulating. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 84696-21-9 →
Auto-generated CPSR Part A draft with source citations
Function
active, wound-healing, anti-inflammatory, collagen-stimulating
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR Expert Panel assessed 9 Centella asiatica-derived ingredients — all concluded safe in present practices of use and concentration, provided formulations are non-sensitizing. Cosmetic ingredient positioned as cosmetic/dermocosmetic in EU under Regulation (EC) 655/2013. Clinical data from 2024 two-center RCT confirms Centella asiatica repairing masks effective and safe as adjunctive rosacea treatment — supports cosmetic efficacy claims without drug classification.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Centella Asiatica Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Face Cream | 0.1–2 | 5 | CIR/VCRP |
| Serum | 0.1–2 | 5 | CIR/VCRP |
Additional Ingredient Properties
10 property records from structured ingredient metadata.
acne
{"cas_number": "84696-21-9", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "p_acnes_mic_ug_per_ml": ">2000", "sebum_reduction_pct_clinical": "0-5", "optimal_ph_for_efficacy": "5.0-7.0", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne"…
anti_aging
{"anti_aging_claim": "anti-wrinkle, barrier-repair, collagen-boosting", "mechanism_of_action": "Triterpenoids, madecassoside, asiaticoside stimulate collagen", "target_skin_layer": "epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "12-20", "clinical_study_duration_weeks": "8", "sample_size": "30", "double_blind": "Yes", "placebo_controlled": "Yes",…
anti_pollution
{"cas_number": "84696-21-9", "ingredient_class": "antioxidant_pollution_shield", "primary_mechanism": "barrier_reinforcement", "pollution_types_targeted": "PM2_5/UV_A", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modul…
comedogenicity_detail
{"comedogenicity_rating": "0", "irritancy_rating": "0", "skin_type_suitability": "all,oily,sensitive,combination,normal,acne-prone,rosacea", "acne_safe": "yes", "source": "Wound healing"}
concentration
{"min_concentration_pct": "0.5", "max_concentration_pct": "3.0", "typical_concentration_pct": "1.5", "product_type": "Toner", "function_at_concentration": "Soothing", "source": "Clinical literature"}
hair_care
{"hair_function": "scalp-care", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "kerati…
pediatric_safety
{"safe_for_newborn_0_6m": "yes", "safe_for_infant_6_12m": "yes", "safe_for_toddler_1_3y": "yes", "safe_for_child_3_12y": "yes", "safe_for_teen_12_18y": "yes", "pediatric_max_concentration_pct": "5.0", "adult_max_concentration_pct": "5.0", "pediatric_dermal_absorption_factor": "normal", "diaper_area_safe": "yes", "pediatric_allergy_prevalence": "low", "banned_in_children_products_eu": "no", "banned…
ph_stability
{"optimal_ph_min": "5.0", "optimal_ph_max": "6.5", "stable_ph_min": "4.5", "stable_ph_max": "7.0", "degrades_above_ph": "7.5", "degrades_below_ph": "4.0", "ph_dependent_function": "Wound healing; stable moderate pH", "formulation_note": "Triterpenoids stable in acidic to neutral", "source": "Formulation literature"}
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Cleaning agent
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Centella Asiatica Extract.
Regulatory Flags
active
striae-prevention
collagen-stimulating
wound-healing
anti-inflammatory
pregnancy-safe
double-blind-evidence
Known Synonyms
gotu kola
Chemical Function
Antioxidant
Humectant
Softener and conditioner
Cleaning agent
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Centella Asiatica Extract allowed in the EU?
Centella Asiatica Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Centella Asiatica Extract do in cosmetics?
Centella Asiatica Extract functions as: active, wound-healing, anti-inflammatory, collagen-stimulating. It is classified as a Active Ingredient in our database. CAS number: 84696-21-9.
Is Centella Asiatica Extract used outside cosmetics?
Centella Asiatica Extract also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Anti-sebum, Antioxidant, Skin Protecting
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(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
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(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
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(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
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(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
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ACANTHOPANAX SENTICOSUS ROOT EXTRACT
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Chemical family
Skin Conditioning, Soothing
Acanthopanax Senticosus Extract
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Azadirachta Indica Bark Extract
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