Good Emollient NOAEL Data GHS Classified

Castor Oil (Ricinus Communis Seed Oil)

Also known as: Castor oil aromatic, Castor oil (Ricinus communis L.), Caswell No. 165B, Cosmetol, EINECS 232-293-8 (+11 more)

INCI: RICINUS COMMUNIS SEED OIL

Castor Oil (Ricinus Communis Seed Oil) (CAS 8001-79-4) is a cosmetic emollient functioning as Emollient. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted, max 16%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 8001-79-4 →

Auto-generated CPSR Part A draft with source citations
CAS Number
8001-79-4
View industrial chemical safety profile →
Function
Emollient
Safety Rating
GOOD

Chemistry & Identifiers

EC Number
232-293-8
ChEBI: CHEBI:140618 UNII: D5340Y2I9G Wikidata: Q337492

Regulatory Status

EU EU Status permitted
EU Max Conc. 16%
US US Status permitted

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Castor Oil (Ricinus Communis Seed Oil).

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

6 study endpoints found for Castor Oil (Ricinus Communis Seed Oil). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 3045 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 7823 mg/kg bw/day oral mouse Subchronic COSMOS_DB
NOAEL 11329 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB
NOAEL 12840 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB
NOAEL =5780 mg/kg bw/day oral Rat subchronic ToxValDB_ECHA_IUCLID
NOAEL =10000 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the gastrointestinal tract.
Long-term Exposure Effects
Repeated or prolonged contact with skin may cause dermatitis.

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Castor Oil (Ricinus Communis Seed Oil) across SCCS product categories, with measured dermal absorption where available.

EPA ToxValDB — Toxicity Values

3 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
NOAEL =10000 mg/kg-day Rat oral - ECHA IUCLID
NOAEL =5780 mg/kg-day Rat oral subchronic ECHA IUCLID
ADI <=0.7 mg/kg Human oral - WHO JECFA ADI

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-caking agent Anti-static agent Binder Defoamer Deodorizer Dispersing agent Drier Emulsifier Flavouring and nutrient Fragrance
Regulatory List Membership (5)
EU Regulated in Personal Care IFRA Fragrance Transparency List EPA Safer Chemical Ingredients List (SCIL) FDA Substances Added to Food (EAFUS) Consumer Product Chemical

Expert Verdict

Expert safety assessment and concern-level summary for Castor Oil (Ricinus Communis Seed Oil).

Regulatory Flags

epa_safer_alternative ifra_fragrance fda_food_additive

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Castor Oil (Ricinus Communis Seed Oil) by CAS number or substance name.

Studies
6
Lowest NOAEL
3045 mg/kg bw/day
Highest NOAEL
12840 mg/kg bw/day
COSMOS_DB ToxValDB_ECHA_IUCLID

Known Synonyms

Castor oil aromatic Castor oil (Ricinus communis L.) Caswell No. 165B Cosmetol EINECS 232-293-8 EPA Pesticide Chemical Code 031608 FEMA No. 2263 Gold bond NCI-C55163 Palma christi oil Ricirus oil Oleum Ricini Ricini oleum Castor oil, aromatic Olio di ricino UNII-D5340Y2I9G

Chemical Function

Softener and conditioner Deodorizer Fragrance Solvent

Regulatory Lists

active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides active_ingredient; Europe; Pesticides active_ingredient; Pesticides

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
castor oil
ChEMBL ID
CHEMBL2109005
Adverse Event Associations
20
View full pharmaceutical profile →

Frequently Asked Questions

Is Castor Oil (Ricinus Communis Seed Oil) safe in cosmetics?

Castor Oil (Ricinus Communis Seed Oil) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 6 toxicological study endpoint(s) are available in our database.

Is Castor Oil (Ricinus Communis Seed Oil) allowed in the EU?

Castor Oil (Ricinus Communis Seed Oil) EU regulatory status: permitted. Maximum allowed concentration: 16%. This is based on EU Regulation 1223/2009 and its amendments.

What does Castor Oil (Ricinus Communis Seed Oil) do in cosmetics?

Castor Oil (Ricinus Communis Seed Oil) functions as: Emollient. It is classified as a Emollient in our database. CAS number: 8001-79-4.

What is the NOAEL for Castor Oil (Ricinus Communis Seed Oil)?

The NOAEL (No Observed Adverse Effect Level) for Castor Oil (Ricinus Communis Seed Oil) is 3045 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 6 study endpoints are available. Source: COSMOS_DB.

Is Castor Oil (Ricinus Communis Seed Oil) used outside cosmetics?

Castor Oil (Ricinus Communis Seed Oil) also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Compliance Tools

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MoS Calculator
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Heavy Metal Limits
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