What is the NOAEL for Castor oil?
Castor oil has 11 NOAEL studies in the database. The lowest reported value is 0.7 mg/kg via oral in Human. Source: ToxValDB_WHO_JECFA_ADI.
NOAEL Data
Cosmetic Ingredient
Castor oil
Also known as: Castor oil aromatic, Castor oil (Ricinus communis L.), Caswell No. 165B, Cosmetol, EINECS 232-293-8 (+11 more)
CAS 8001-79-4
Castor oil (CAS 8001-79-4) is a chemical substance. Key regulatory status: 41 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ILO ICSC.
View cosmetic safety profile for Castor Oil (Ricinus Communis Seed Oil) →
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
41
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
Castor oil
CAS Number
8001-79-4
DTXSID
DTXSID7024742
Synonyms
Castor oil aromaticCastor oil (Ricinus communis L.)Caswell No. 165BCosmetolEINECS 232-293-8EPA Pesticide Chemical Code 031608FEMA No. 2263Gold bondNCI-C55163Palma christi oilRicirus oilOleum Ricini
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the gastrointestinal tract. |
| Long-term Effects | Repeated or prolonged contact with skin may cause dermatitis. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Softener and conditionerDeodorizerFragranceSolventHumectantBinderProcessing aids not otherwise specifiedPlasticizerDispersing agentAnti-static agentDefoamerEmulsifierThickening agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
41 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| Europe; Personal care - make-up and related | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - make-up and related | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| consumer_product; Europe | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=0.7 | mg/kg | ADI | oral | Human | ToxValDB_WHO_JECFA_ADI |
| D5340Y2I9G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| D5340Y2I9G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| D5340Y2I9G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| D5340Y2I9G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3045 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =5780 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 7823 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| =10000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 11329 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 12840 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 11 of 11 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
16%
Category
emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
castor oil
ChEMBL Phase
Not listed
Adverse Events
20
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Castor oil?
Castor oil appears on 14 regulatory/inventory lists including active_ingredient; Pesticides, inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, and 11 more. Source: EPA CPDat.
Is Castor oil used in cosmetics?
Yes, Castor oil is also indexed as a cosmetic ingredient under the name Castor Oil (Ricinus Communis Seed Oil). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Castor oil come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Castor oil used outside industrial chemicals?
Castor oil also appears in cosmetics, pharmaceutical, cannabis databases.