Is CAPSICUM ANNUUM EXTRACT safe in cosmetics?
CAPSICUM ANNUUM EXTRACT has a safety rating of "GOOD" in our database. EU status: permitted. US status: restricted. 5 toxicological study endpoint(s) are available in our database.
CAPSICUM ANNUUM EXTRACT
CAPSICUM ANNUUM EXTRACT (CAS 84625-29-6) is a cosmetic cosmetic ingredient functioning as Fragrance, Skin Conditioning, Tonic. Reported NOAEL =2052 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 84625-29-6 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance, Skin Conditioning, Tonic
Safety Rating
GOOD
Chemistry & Identifiers
EC Number
283-403-6
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
CIR: SQ - IJT 26(Suppl. 1):3-106, 2007
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
5 study endpoints found for CAPSICUM ANNUUM EXTRACT. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =2052 mg/kg bw/day | oral | Rat | chronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =2324 mg/kg bw/day | oral | Rat | chronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =2388 mg/kg bw/day | oral | Rat | chronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =2948.4 mg/kg bw/day | oral | Rat | subchronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =3197.4 mg/kg bw/day | oral | Rat | subchronic | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-dandruff
Antioxidant
Astringent
Biocide
Humectant
No specific technical function
Softener and conditioner
Regulatory List Membership (2)
EU Restricted for Children (Cosmetics)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for CAPSICUM ANNUUM EXTRACT.
Regulatory Flags
cosing-sourced
eu-permitted
skin-conditioning
fragrance
needs-enrichment
eu_children_restricted
ifra_fragrance
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to CAPSICUM ANNUUM EXTRACT by CAS number or substance name.
Studies
5
Lowest NOAEL
2052 mg/kg bw/day
Highest NOAEL
3197.4 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Chemical Function
Biocide
Antioxidant
Humectant
Astringent
Deodorizer
Softener and conditioner
Regulatory Lists
children
Europe
Personal care
children
Europe
Personal care - dental care - toothpaste
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is CAPSICUM ANNUUM EXTRACT allowed in the EU?
CAPSICUM ANNUUM EXTRACT EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does CAPSICUM ANNUUM EXTRACT do in cosmetics?
CAPSICUM ANNUUM EXTRACT functions as: Fragrance, Skin Conditioning, Tonic. It is classified as a cosmetic ingredient in our database. CAS number: 84625-29-6.
What is the NOAEL for CAPSICUM ANNUUM EXTRACT?
The NOAEL (No Observed Adverse Effect Level) for CAPSICUM ANNUUM EXTRACT is =2052 mg/kg bw/day based on a chronic study via oral route in Rat. A total of 5 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is CAPSICUM ANNUUM EXTRACT used outside cosmetics?
CAPSICUM ANNUUM EXTRACT also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CAPSICUM ANNUUM EXTRACT compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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