Moderate Cosmetic Ingredient NOAEL Data

Capramide DEA

Also known as: N,N-bis(2-hydroxyethyl)-, Decanamide, N,N-bis(2-hydroxyethyl)-, Capric acid diethanolamide, N,N-Diethylolcapramide, UNII-SHH19DQ1DH

INCI: CAPRAMIDE DEA

Capramide DEA (CAS 136-26-5) is a cosmetic cosmetic ingredient functioning as Surfactant – Foam Booster, Viscosity Increasing Agent. Reported NOAEL =200 mg/kg/d in rat (CIR_vision_codex); EU Regulation 1223/2009 status: restricted, max 0.5%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 136-26-5 →

Auto-generated CPSR Part A draft with source citations
Function
Surfactant – Foam Booster, Viscosity Increasing Agent
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C14H29NO3
MW
259.38 g/mol
PubChem CID
61081
IUPAC Name
N,N-bis(2-hydroxyethyl)decanamide
InChIKey
BPXGKRUSMCVZAF-UHFFFAOYSA-N

Regulatory Status

EU EU Status restricted
EU Max Conc. 0.5%
US US Status permitted
US Notes Conditional — MoS adequate only when nitrosamine-free formulation is verified and concentration limits respected

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Capramide DEA.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Capramide DEA. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =200 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =200 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =200 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =200 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =380 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =380 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =380 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =380 mg/kg/d oral rat developmental toxicity CIR_vision_codex
NOAEL =1000 mg/kg/d oral rat repeated dose toxicity CIR_vision_codex
NOAEL =1000 mg/kg/d oral rat repeated dose toxicity CIR_vision_codex

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-static agent Foamant Softener and conditioner Surfactant (surface active agent) Viscosity modifier

Expert Verdict

Expert safety assessment and concern-level summary for Capramide DEA.

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Capramide DEA by CAS number or substance name.

Studies
12
Lowest NOAEL
200 mg/kg/d
Highest NOAEL
1000 mg/kg/d
CIR_vision_codex

Known Synonyms

N,N-bis(2-hydroxyethyl)- Decanamide, N,N-bis(2-hydroxyethyl)- Capric acid diethanolamide N,N-Diethylolcapramide UNII-SHH19DQ1DH

Chemical Function

Surfactant (surface active agent) Anti-static agent Viscosity modifier Softener and conditioner Foamant

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Capramide DEA safe in cosmetics?

Capramide DEA has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.

Is Capramide DEA allowed in the EU?

Capramide DEA EU regulatory status: restricted. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.

What does Capramide DEA do in cosmetics?

Capramide DEA functions as: Surfactant – Foam Booster, Viscosity Increasing Agent. It is classified as a cosmetic ingredient in our database. CAS number: 136-26-5.

What is the NOAEL for Capramide DEA?

The NOAEL (No Observed Adverse Effect Level) for Capramide DEA is =200 mg/kg/d based on a developmental toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: CIR_vision_codex.

Is Capramide DEA used outside cosmetics?

Capramide DEA also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Capramide DEA have different safety status in cosmetics vs industrial chemicals?

Capramide DEA is classified GHS Danger (H315, H318, H410, H319) in the chemicals database but is restricted in EU cosmetics at max 0.5%.

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