Is Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract) safe in cosmetics?
Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Active Ingredient
Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract)
Also known as: Dextran 40,70,110, Dextranum 40,70, EINECS 232-677-5, Low molecular dextran-L, Polyglucinum (+15 more)
INCI: CAPIXYL
Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract) (CAS 9004-54-0) is a cosmetic active ingredient functioning as Antioxidant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 9004-54-0 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No monograph exists
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract).
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization AOP Dashboard
Adverse Outcome Pathway data across 5 assays (DPRA, KeratinoSens, hCLAT, LLNA, NESIL) aggregated from public sources.
KeratinoSens IC50
2000 µM
GHS: inconclusive
Source: KS: Urbisch et al. 2015 [DOI:10.1016/j.yrtph.2014.12.008]
Additional Ingredient Properties
2 property records from structured ingredient metadata.
concentration
{"min_concentration_pct": "1.0", "max_concentration_pct": "5.0", "typical_concentration_pct": "3.0", "product_type": "Hair Serum", "function_at_concentration": "Hair growth, DHT blocking", "source": "Supplier TDS (Lucas Meyer)"}
hair_care
{"hair_function": "scalp-care", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "kerati…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Binder
Filler
Processing aids not otherwise specified
Surface modifier
Thickening agent
Viscosity modifier
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract).
Regulatory Flags
fda_food_additive
Known Synonyms
Dextran 40,70,110
Dextranum 40,70
EINECS 232-677-5
Low molecular dextran-L
Polyglucinum
Dextranum
UNII-7SA290YK68
UNII-K3R6ZDH4DU
UNII-ZNJ8R24I7Z
UNII-65DL069QBP
UNII-21C3YS80Q6
UNII-42N66Q2197
UNII-PD6VU01UVN
UNII-V7031C06AY
UNII-E8A73H7RG1
UNII-05Q25F6XJ3
UNII-P8272ET3N5
UNII-41Z0077J45
UNII-7C8S056150
UNII-B854H05S7D
Chemical Function
Viscosity modifier
Binder
Filler
Processing aids not otherwise specified
Thickening agent
Surface modifier
Regulatory Lists
Canada; consumer_product; Substances in Products - Canada (4/2014)
Canada; consumer_product; Substances in Products - Canada (4/2014)
pharmaceutical
Canada; pharmaceutical
Canada; pharmaceutical
pharmaceutical
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract) allowed in the EU?
Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract) do in cosmetics?
Capixyl (Acetyl Tetrapeptide-3, Trifolium Pratense Extract) functions as: Antioxidant. It is classified as a Active Ingredient in our database. CAS number: 9004-54-0.
Compliance Tools
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Substance Compliance
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MoS Calculator
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