Is CALENDULA OFFICINALIS FLOWER EXTRACT safe in cosmetics?
CALENDULA OFFICINALIS FLOWER EXTRACT has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. This ingredient has been reviewed by cir.
CALENDULA OFFICINALIS FLOWER EXTRACT
Also known as: EINECS 283-949-5, Garden Marigold extracts
CALENDULA OFFICINALIS FLOWER EXTRACT (CAS 84776-23-8) is a cosmetic active ingredient functioning as skin-conditioning, anti-inflammatory, soothing. EU Regulation 1223/2009 status: permitted; 1 safety opinion reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 84776-23-8 →
Auto-generated CPSR Part A draft with source citations
Function
skin-conditioning, anti-inflammatory, soothing
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR: calendula extract safe in cosmetics at present practices of use; anti-inflammatory properties beneficial for barrier-compromised lip skin; particularly valuable in lip care for chemotherapy patients (mucositis) and sensitive lip conditions; no FDA restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CALENDULA OFFICINALIS FLOWER EXTRACT.
Calculate MoS for your specific formulation with the MoS Calculator.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
cir
7 January 2001
Verdict: unknown
Sensitization Profile
Contact sensitization data for CALENDULA OFFICINALIS FLOWER EXTRACT based on clinical patch test studies and IFRA standards.
Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.5%
Cross-reactivity Group
compositae-group
Reaction Type
contact-dermatitis
Source: IVDK; ESSCA; NACDG
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
6 property records from structured ingredient metadata.
allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "botanical", "cross_reactivity_group": "compositae-group", "patch_test_frequency_pct": "0.5", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "IVDK; ESSCA; NACDG"}
anti_aging
{"anti_aging_claim": "anti-inflammatory, barrier-repair", "mechanism_of_action": "Bioactive phytochemicals, antioxidant compounds", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "No", "wrinkle_reduction_pct": "4-8", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": "Phytotherapy…
anti_pollution
{"cas_number": "84776-23-8", "ingredient_class": "antioxidant_pollution_shield", "primary_mechanism": "barrier_reinforcement", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation…
depigmentation
{"cas_number": "84776-23-8", "ingredient_class": "anti_inflammatory_brightener", "primary_mechanism_of_action": "Triterpenoids reduce PIH and inflammation", "secondary_mechanisms": "Variable", "molecular_target": "other", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduction_pct_clinical": "15-30", "ons…
self_tanning
{"cas_number": "84776-23-8", "ingredient_class": "tan_extender", "tanning_mechanism": "other", "color_development_onset_hours": "0.0", "full_color_development_hours": "0", "color_duration_days": "3", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "0", "pH_dependent_color": "no", "formaldehyde_release_concern": "no", "formaldehyde_release_ppm": "0", "AGE_formation_conc…
solubility_hlb
{"water_soluble": "yes", "oil_soluble": "partial", "soluble_in": "water, propylene glycol, ethanol", "insoluble_in": "oils", "log_p": "-1.0", "appearance": "amber to brown liquid", "source": "Symrise"}
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Deodorizer
Flavouring and nutrient
Fragrance
Humectant
Processing aids not otherwise specified
Softener and conditioner
Regulatory List Membership (2)
EU Regulated in Personal Care
EU Restricted for Children (Cosmetics)
Expert Verdict
Expert safety assessment and concern-level summary for CALENDULA OFFICINALIS FLOWER EXTRACT.
Regulatory Flags
cir-approved
cosmos-eligible
natural
vegan
lip-safe
oral-safe
anti-inflammatory
soothing
mucositis-care
chemotherapy-lip-care
asteraceae-caution
ecocert-eligible
eu_children_restricted
Known Synonyms
EINECS 283-949-5
Garden Marigold extracts
Chemical Function
Softener and conditioner
Humectant
Deodorizer
Flavouring and nutrient
Regulatory Lists
Europe; Personal care
children; Europe; Personal care
children; Europe; Personal care - general moisturizing - hand/body lotion
children; Europe; Personal care - specialized bath products - bubble bath
children; Europe; Personal care - dental care - toothpaste
Canada; Personal care; Substances in PCP - Canada (4/2014)
Europe; Personal care
Europe; Personal care
Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is CALENDULA OFFICINALIS FLOWER EXTRACT allowed in the EU?
CALENDULA OFFICINALIS FLOWER EXTRACT EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does CALENDULA OFFICINALIS FLOWER EXTRACT do in cosmetics?
CALENDULA OFFICINALIS FLOWER EXTRACT functions as: skin-conditioning, anti-inflammatory, soothing. It is classified as a Active Ingredient in our database. CAS number: 84776-23-8.
Is CALENDULA OFFICINALIS FLOWER EXTRACT used outside cosmetics?
CALENDULA OFFICINALIS FLOWER EXTRACT also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CALENDULA OFFICINALIS FLOWER EXTRACT compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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