Calcium Tartrate

INCI: CALCIUM TARTRATE

Calcium Tartrate (CAS 3164-34-9) is a cosmetic cosmetic ingredient functioning as Skin conditioning, buffering agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 3164-34-9 →

Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, buffering agent
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C4H4CaO6
MW
188.15 g/mol
EC Number
221-621-5
PubChem CID
9815471
IUPAC Name
calcium (2R,3R)-2,3-dihydroxybutanedioate
InChIKey
GUPPESBEIQALOS-ZVGUSBNCSA-L

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Adequate — No systemic toxicity concern at cosmetic use levels

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Calcium Tartrate.

Calculate MoS for your specific formulation with the MoS Calculator.

EPA ToxValDB — Toxicity Values

10 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
NOAEL =3100 mg/kg-day Rat oral chronic EFSA
LD50 >2000 mg/kg Rat oral - ECHA IUCLID
LD50 ~4109 mg/kg Mouse oral - ECHA IUCLID
LD50 =4109 mg/kg Mouse oral - ECHA IUCLID
LD50 =920 mg/kg Rat oral - ECHA IUCLID
LD50 >5000 mg/kg Rat oral - ECHA IUCLID
LD50 >5000 mg/kg Rat oral - ECHA IUCLID
LD50 ~920 mg/kg Rat oral - ECHA IUCLID
LD50 >=2000 mg/kg Rat oral - ECHA IUCLID
LD50 <=5000 mg/kg Rat oral - ECHA IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Regulatory (2)
JECFA Evaluation
CALCIUM L(+)-TARTRATE | 1983 | NO ADI ALLOCATED | TRS 696-JECFA 27/28 | NOT PREPARED
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
EU Food Improvement
Food additives
Source: EU Food Improvement Agents

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for Calcium Tartrate.

Chemical Function

Softener and conditioner

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Calcium Tartrate safe in cosmetics?

Calcium Tartrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Calcium Tartrate allowed in the EU?

Calcium Tartrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Calcium Tartrate do in cosmetics?

Calcium Tartrate functions as: Skin conditioning, buffering agent. It is classified as a cosmetic ingredient in our database. CAS number: 3164-34-9.

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