Is Calcium Glucoheptonate safe in cosmetics?
Calcium Glucoheptonate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Calcium Glucoheptonate
Also known as: Calcium bis((3R,4S,5R,6R)-2,3,4,5,6,7-hexahydroxyheptanoate), D-gluco-Heptonic acid, calcium salt, (2ξ)- (2:1), D-gluco-Heptonic acid, calcium salt (2:1), (2ξ)-, Glucoheptonic acid, calcium salt (2:1), Calcihept (+6 more)
INCI: CALCIUM GLUCOHEPTONATE
Calcium Glucoheptonate (CAS 29039-00-7) is a cosmetic cosmetic ingredient functioning as Skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 29039-00-7 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
calcium bis((3R,4S,5R,6R)-2,3,4,5,6,7-hexahydroxyheptanoate)
InChIKey
FATUQANACHZLRT-KMRXSBRUSA-L
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically CIR-reviewed for cosmetics; FDA-approved pharmaceutical (calcium supplement — DrugBank DB00326); used to treat hypocalcemia
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Calcium Glucoheptonate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Calcium Glucoheptonate.
Known Synonyms
Calcium bis((3R,4S,5R,6R)-2,3,4,5,6,7-hexahydroxyheptanoate)
D-gluco-Heptonic acid, calcium salt, (2ξ)- (2:1)
D-gluco-Heptonic acid, calcium salt (2:1), (2ξ)-
Glucoheptonic acid, calcium salt (2:1)
Calcihept
Calcium heptagluconate
Glucoheptonic acid calcium salt
EC No.: 249-383-8
EINECS 249-383-8
calcium bis[(2ξ)-D-gluco-heptonate]
249-383-8
Chemical Function
Softener and conditioner
Regulatory Lists
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
calcium glucoheptonate
ChEMBL ID
CHEMBL1237066
Adverse Event Associations
135
Frequently Asked Questions
Is Calcium Glucoheptonate allowed in the EU?
Calcium Glucoheptonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Calcium Glucoheptonate do in cosmetics?
Calcium Glucoheptonate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 29039-00-7.
Is Calcium Glucoheptonate used outside cosmetics?
Calcium Glucoheptonate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Calcium Glucoheptonate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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