Is Caffeoyl Hexapeptide-65 safe in cosmetics?
Caffeoyl Hexapeptide-65 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Caffeoyl Hexapeptide-65
INCI: CAFFEOYL HEXAPEPTIDE-65
Caffeoyl Hexapeptide-65 (CAS Not assigned / Not publicly available) is a cosmetic cosmetic ingredient functioning as Antimicrobial, Antioxidant, Skin Conditioning, Skin Protecting. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS Not assigned / Not publicly available →
Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial, Antioxidant, Skin Conditioning, Skin Protecting
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not established
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Caffeoyl Hexapeptide-65.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Caffeoyl Hexapeptide-65.
Regulatory Flags
potential-allergen
Frequently Asked Questions
Is Caffeoyl Hexapeptide-65 allowed in the EU?
Caffeoyl Hexapeptide-65 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Caffeoyl Hexapeptide-65 do in cosmetics?
Caffeoyl Hexapeptide-65 functions as: Antimicrobial, Antioxidant, Skin Conditioning, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned / Not publicly available.
Compliance Tools
Check Caffeoyl Hexapeptide-65 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2-O-Ethyl Ascorbic Acid
Excellent
Same category
Softener and conditioner
3-Glyceryl Ascorbate
Excellent
Same category
Antioxidant, Humectant, Skin Conditio...
Allantoin Ascorbate
Excellent
Same category
Antioxidant, Skin Conditioning, Skin ...
Aloe Vera Extract
Excellent
Same category
Skin Conditioning, Antioxidant
Althaea Officinalis Callus Culture Extract
Excellent
Same category
Antioxidant, skin protectant
Amaranthus Caudatus Seed Oil
Excellent
Same category
Emollient, skin conditioning, antioxi...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(SH-Pentapeptide-10 6-Aminocaprooyl SH-Pentapeptide-11) SP
Moderate
Similar safety
Skin/hair conditioning (peptide-based...
1,2,3,4,4a,5,6,7-Octahydro-2,5,5-Trimethyl-2-Naphthol
Moderate
Similar safety
Fragrance ingredient
CALCIUM ASCORBATE
Good
Browse nearby
Antioxidant, Skin Conditioning
CALCIUM BEHENATE
Good
Browse nearby
Anticaking, Opacifying, Viscosity Con...
CALCIUM CARBONATE/CALCIUM HYDROXIDE/CALCIUM OXIDE/CLAY/ILLITE/ORTHOCLASE/OYSTER SHELL POWDER/QUARTZ POWDER/VERMICULITE/ZEOLITE EXTRACT
Good
Browse nearby
Humectant, Skin Conditioning, Skin Co...
Is Caffeoyl Hexapeptide-65 in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Caffeoyl Hexapeptide-65 in your formulation.