Is Butyl Hexanoate safe in cosmetics?
Butyl Hexanoate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Butyl Hexanoate
Also known as: BRN 1754426, n-Butyl hexanoate, EINECS 210-964-6, FEMA No. 2201, NSC 4022 (+8 more)
INCI: BUTYL HEXANOATE
Butyl Hexanoate (CAS 626-82-4) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 626-82-4 →
Auto-generated CPSR Part A draft with source citations
Chemistry & Identifiers
IUPAC Name
butyl hexanoate
InChIKey
RPRPDTXKGSIXMD-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Adequate at standard fragrance concentrations; IFRA guidelines applicable
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Butyl Hexanoate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 675 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
162
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
BUTYL CAPROATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/52 | FAS 40-JECFA 49/297
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
BUTYL HEXANOATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/52 | FAS 40-JECFA 49/297
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Butyl Hexanoate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
BRN 1754426
n-Butyl hexanoate
EINECS 210-964-6
FEMA No. 2201
NSC 4022
UNII-EBK588Q27T
Butyl caproate
Butyl caprylate
Butyl ester of hexanoic acid
FEMA 2201
N-Butyl N-hexanoate
N-Butyl caproate
N-Caproic acid N-butyl ester
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Butyl Hexanoate allowed in the EU?
Butyl Hexanoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Butyl Hexanoate do in cosmetics?
Butyl Hexanoate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 626-82-4.
Is Butyl Hexanoate used outside cosmetics?
Butyl Hexanoate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Butyl Hexanoate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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