Is Butyl Cinnamate safe in cosmetics?
Butyl Cinnamate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Butyl Cinnamate
Also known as: 2-Propenoic acid, 3-phenyl-, butyl ester, 4-09-00-02008, BRN 2328067, n-Butyl cinnamate, Butyl phenylacrylate (+11 more)
INCI: BUTYL CINNAMATE
Butyl Cinnamate (CAS 538-65-8) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient, UV absorber (minor). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 538-65-8 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient, UV absorber (minor)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
butyl (E)-3-phenylprop-2-enoate
InChIKey
OHHIVLJVBNCSHV-MDZDMXLPSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Adequate with IFRA-compliant use levels
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Butyl Cinnamate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2700 | - | - |
Additional Ingredient Properties
1 property record from structured ingredient metadata.
fragrance_ifra
{"cas_number": "538-65-8", "ifra_amendment_number": "49", "ifra_restriction_type": "Restricted", "ifra_max_use_level_category_1_pct": "0.11", "ifra_max_use_level_category_4_pct": "1.8", "ifra_max_use_level_category_7_pct": "0.26", "ifra_max_use_level_category_11_pct": "0.052", "eu_allergen_declaration_required": "No", "eu_26_allergens_list": "No", "sccs_opinion_available": "Yes", "sensitization_po…
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
663
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
BUTYL CINNAMATE | 2000 | No safety concern at current levels of intake when used as a flavouring agent | TRS 901-JECFA 55/22 | FAS 46-JECFA 55/79
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Butyl Cinnamate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
2-Propenoic acid, 3-phenyl-, butyl ester
4-09-00-02008
BRN 2328067
n-Butyl cinnamate
Butyl phenylacrylate
n-Butyl phenylacrylate
Butyl 3-phenylpropenoate
Butyl 3-phenyl-2-propenoate
Butyl-beta-phenylacrylate
Cinnamic acid n-butyl ester
EINECS 208-699-6
Eliminoxy
FEMA No. 2192
NSC 71966
Cinnamate de n-butyle
UNII-05Q793M6Z5
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BUTYL CINNAMATE
ChEMBL ID
CHEMBL1911049
Frequently Asked Questions
Is Butyl Cinnamate allowed in the EU?
Butyl Cinnamate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Butyl Cinnamate do in cosmetics?
Butyl Cinnamate functions as: Fragrance ingredient, UV absorber (minor). It is classified as a cosmetic ingredient in our database. CAS number: 538-65-8.
Is Butyl Cinnamate used outside cosmetics?
Butyl Cinnamate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Butyl Cinnamate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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