Is Butyl Anthranilate safe in cosmetics?
Butyl Anthranilate has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
Butyl Anthranilate
Also known as: Benzoic acid, 2-amino-, butyl ester, Anthranilic acid, butyl ester (6CI,7CI,8CI), 2-Aminobenzoic acid butyl ester, EINECS 231-816-7, FEMA No. 2181 (+7 more)
INCI: BUTYL ANTHRANILATE
Butyl Anthranilate (CAS 7756-96-9) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient, denaturant. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7756-96-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Butyl Anthranilate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H335).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance ingredient, denaturant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
butyl 2-aminobenzoate
InChIKey
HUIYGGQINIVDNW-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Requires ingredient-specific MoS calculation; insufficient published aggregate exposure data
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Butyl Anthranilate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2592 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
1536
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
BUTYL 2-AMINOBENZOATE | 2005 | No safety concern at current levels of intake when used as a flavouring agent | TRS 934-JECFA 65/54 | FAS 56-JECFA 65
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
BUTYL ANTHRANILATE | 2005 | No safety concern at current levels of intake when used as a flavouring agent | TRS 934-JECFA 65/54 | FAS 56-JECFA 65
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Butyl Anthranilate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
Benzoic acid, 2-amino-, butyl ester
Anthranilic acid, butyl ester (6CI,7CI,8CI)
2-Aminobenzoic acid butyl ester
EINECS 231-816-7
FEMA No. 2181
NSC 406509
UNII-73DAT3M81O
Anthranilic acid, butyl ester
Butyl 2-aminobenzoate
Butyl o-aminobenzoate
n-Butyl anthranilate
n-Butyl o-aminobenzoate
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BUTYL 2-AMINOBENZOATE
ChEMBL ID
CHEMBL1558498
Frequently Asked Questions
Is Butyl Anthranilate allowed in the EU?
Butyl Anthranilate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Butyl Anthranilate do in cosmetics?
Butyl Anthranilate functions as: Fragrance ingredient, denaturant. It is classified as a cosmetic ingredient in our database. CAS number: 7756-96-9.
Is Butyl Anthranilate used outside cosmetics?
Butyl Anthranilate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Butyl Anthranilate have different safety status in cosmetics vs industrial chemicals?
Butyl Anthranilate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H335).
Compliance Tools
Check Butyl Anthranilate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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